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Azaserine
Known as:
L-Serine, diazoacetate (ester)
, L-Azaserine
, AZAS
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A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine…
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National Institutes of Health
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Related topics
Related topics
14 relations
Broader (5)
Antibiotics, Antineoplastic
Antifungal Agents
Antimetabolites, Antineoplastic
Azo Compounds
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In Blood
NCIt Antineoplastic Agent Terminology
agonists
analogs & derivatives
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Narrower (1)
P-165
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1994
1994
Synthesis of heterocyclic natural products: Model studies towards diazonamide A
C. Moody
,
K. Doyle
,
M. Elliott
,
T. Mowlem
1994
Corpus ID: 7589335
Abstract
1987
1987
Effect of Orchiectomy and Testosterone on the Early Stages of Azaserine‐Induced Pancreatic Carcinogenesis in the Rat
E. Lhoste
,
B. Roebuck
,
J. Stern
,
D. Longnecker
Pancreas
1987
Corpus ID: 20466068
The incidence of carcinoma of the pancreas is higher among men than women. It is also higher among male than female carcinogen…
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1985
1985
Dietary intervention during the postdosing phase of L-azaserine-induced preneoplastic lesions.
T. O’Connor
,
B. Roebuck
,
T. Campbell
Journal of the National Cancer Institute
1985
Corpus ID: 39042983
The effects of intervention by diets with high or low levels of dietary fat on the development of preneoplastic pancreatic…
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1984
1984
Mechanism of inactivation of chymotrypsin by 3-benzyl-6-chloro-2-pyrone.
M. Gelb
,
R. Abeles
Biochemistry
1984
Corpus ID: 44893796
The mechanism of inactivation of chymotrypsin by 3-benzyl-6-chloro-2-pyrone has been studied. Chloride analysis of the…
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1980
1980
Pathologic and biochemical effects of azaserine in inbred Wistar/Lewis rats and noninbred CD-1 mice.
B. Roebuck
,
H. Lilja
,
T. Curphey
,
D. Longnecker
Journal of the National Cancer Institute
1980
Corpus ID: 25314716
Inbred W/LEW rats and noninbred CD-1 mice were compared for responsiveness to induction of pancreatic adenocarcinomas by…
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Highly Cited
1973
Highly Cited
1973
Studies on possible routes of ammonium assimilation in soybean root nodule bacteroids.
S. Dunn
,
R. Klucas
Canadian Journal of Microbiology (print)
1973
Corpus ID: 38369028
Glutamine amide–2-oxoglutarate aminotransferase NAD+ oxidoreductase (GOGAT), glutamine synthetase (GS), glutamate dehydrogenase…
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1959
1959
ACTION OF AZASERINE ON ESCHERICHIA COLI
L. Kaplan
,
H. C. Reilly
,
C. Stock
Journal of Bacteriology
1959
Corpus ID: 20268945
Azaserine (O-diazoacetyl-L-serine) was first isolated from a crude broth filtrate of Streptomyces fragilis and found to possess…
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1959
1959
Study of Inhibition of Azaserine and Diazo-oxo-norleucine (DON) on the Algae Scenedesmus and Chlorella1
P. P. D. Meulen
,
J. .. Bassham
1959
Corpus ID: 101428956
The effects of azaserine and DON ( d1aza-oxo-norleucine) on the metabolism of the el.gae Scened.eo:nro.s and. ChloreUa. during…
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Highly Cited
1957
Highly Cited
1957
Effects of combinations of azaserine and of 6-diazo-5-oxo-L-norleucine with purine analogs and other antimetabolites on the growth of two mouse mammary carcinomas.
G. Tarnowski
,
C. Stock
Cancer Research
1957
Corpus ID: 25628375
1. Combined treatment of mice bearing the RC mammary carcinoma with azaserine or DON, on the one hand, and 6-mercaptopurine, 6…
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1956
1956
The influence of azaserine and 6-mercaptopurine on the in vivo metabolism of ascites tumor cells.
J. F. Fernandes
,
G. A. Lepage
,
A. Lindner
Cancer Research
1956
Corpus ID: 7152714
Several chemical agents are now available which have shown activity in inhibiting or destroying certain experimental cancers…
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