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Antimetabolites, Antineoplastic

Known as: ANTINEOPLASTICS,ANTIMETABOLITES, Antineoplastic Antimetabolites, [AN300] ANTINEOPLASTICS,ANTIMETABOLITES 
Antimetabolites that are useful in cancer chemotherapy.
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (44)

10 ML Fluorouracil 50 MG/ML Injection2 ML Methotrexate 25 MG/ML Injection20 ML Fluorouracil 50 MG/ML Injection3-deazaguanine
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Broader (1)

Antimetabolites
Folic Acid AntagonistsIn Bloodaspects of radiation effectschemical synthesis
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1999
1999
Preclinical Pharmacology Studies and the Clinical Development of a Novel Multitargeted Antifolate, MTA (LY231514)
Since the early 1950s, extensive research efforts have been devoted to the discovery and development of antifolate… Expand
1998
1998
Correction of lower eyelid retraction in thyroid eye disease: a randomised controlled trial of retractor tenotomy with adjuvant antimetabolite versus scleral graft
BACKGROUND/AIMS Lower eyelid retraction in thyroid eye disease contributes to ocular discomfort and an unsightly appearance… Expand
Highly Cited
1997
Highly Cited
1997
Cell cycle effects of antifolate antimetabolites: implications for cytotoxicity and cytostasis
Abstract Purpose: Cell cycle-related events in CCRF-CEM lymphocytic leukemia cells were examined subsequent to inhibition of… Expand
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Review
1991
Review
1991
Polyamines: from molecular biology to clinical applications.
The polyamines putrescine, spermidine and spermine represent a group of naturally occurring compounds exerting a bewildering… Expand
1986
1986
Noninvasive spectroscopic analysis of fluoropyrimidine metabolism in cultured tumor cells.
Nuclear magnetic resonance spectroscopy is a technique that may be used noninvasively to follow the intracellular metabolism of… Expand
1985
1985
Antitumor effects of two polyamine antimetabolites combined with mitomycin C on human stomach cancer cells xenotransplanted into nude mice
The antitumor effects of alpha‐difluoromethylornithine (DFMO), methylglyoxal‐bis‐guanylhydrazone (MGBG) and mitomycin C (MMC… Expand
1985
1985
Effects of inhibitors of polyamine biosynthesis on the growth and melanogenesis of murine melanoma cells.
Both 2-difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase (EC 4.1.1.17), and methylglyoxal bis… Expand
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1983
1983
Stimulation of melanotic expression in murine melanoma cells exposed to polyamine antimetabolites.
An exposure of cultured Cloudman S91 melanoma cells to inhibitors of polyamine biosynthesis, 2-difluoromethylornithine (DFMO) and… Expand
Review
1981
Review
1981
Use of polyamine antimetabolites in experimental tumours and in human leukemia.
1971
1971
Immunosuppressive therapy of asthma.
Eleven asthmatic men were treated with the antimetabolites thioguanosine or 6-mercaptopurine. Eight completed 12 weeks of… Expand
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