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3-deazaguanine

Known as: 6-aminoimidazo(4,5-c)pyridin-4(5H)-one, Deazaguanine, Dezaguanine 
A purine nucleoside analogue with antineoplastic and antiviral activities. By replacing guanine, dezaguanine incorporates into DNA and inhibits de… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

AntimetabolitesAntimetabolites, AntineoplasticGuanine

Narrower (1)

CI-908
Dezaguanine Mesylateanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Evaluation of cell viability dyes in antiviral assays with RNA viruses that exhibit different cytopathogenic properties.
2016
2016
Susceptibilities of enterovirus D68, enterovirus 71, and rhinovirus 87 strains to various antiviral compounds.
Review
2016
Review
2016
Deazaguanine derivatives, examples of crosstalk between RNA and DNA modification pathways
ABSTRACT Seven-deazapurine modifications were thought to be highly specific of tRNAs, but have now been discovered in DNA of… 
2009
2009
Molecular recognition of a thymine bulge by a high affinity, deazaguanine-based hydrogen-bonding ligand.
7-Deazaguanine (7-DeG) was developed as a hydrogen-bonding module capable of enhanced recognition of uracil (U) and thymine (T… 
Highly Cited
2003
Highly Cited
2003
Dynamics and energetics of single-step hole transport in DNA hairpins.
The dynamics of single-step hole transport processes have been investigated in a number of DNA conjugates possessing a… 
Highly Cited
1998
Highly Cited
1998
DNA-mediated electron transfer from a modified base to ethidium: pi-stacking as modulator of reactivity.
1995
1995
Use of lactate dehydrogenase to evaluate the anti-viral activity against influenza A virus.
Highly Cited
1989
Highly Cited
1989
Inhibitory effect of selected antiviral compounds on measles (SSPE) virus replication in vitro.
Highly Cited
1976
Highly Cited
1976
Synthesis of 3-deazaguanine, 3-deazaguanosine, and 3-deazaguanylic acid by a novel ring closure of imidazole precursors.
1957
1957
Deazapurines as growth inhibitors.
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