Complement Inactivating Agents

Known as: Complement Inhibitors, complement inhibitor, Inhibiting Agents, Complement 
Compounds that negatively regulate the cascade process of COMPLEMENT ACTIVATION. Uncontrolled complement activation and resulting cell lysis is… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Certain pathogens recruit host complement inhibitors such as factor H (fH) to evade the immune system. Microbial complement… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Dengue virus infection causes an array of symptoms ranging from dengue fever (DF) to dengue hemorrhagic fever (DHF… (More)
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Highly Cited
2007
Highly Cited
2007
The complement system provides critical immunoprotective and immunoregulatory functions but uncontrolled complement activation… (More)
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Highly Cited
2006
Highly Cited
2006
Two newly discovered immune modulators, chemotaxis inhibitory protein of Staphylococcus aureus (CHIPS) and staphylococcal… (More)
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Highly Cited
2006
Highly Cited
2006
Ischemia/reperfusion (I/R) of several organs results in complement activation, but the kidney is unique in that activation after… (More)
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Highly Cited
2005
Highly Cited
2005
The complement system is pivotal in host defense but also contributes to tissue injury in several diseases. The assembly of C3… (More)
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Highly Cited
2002
Highly Cited
2002
The Lyme disease spirochete, Borrelia burgdorferi, is capable of infecting a wide variety of vertebrates. This broad host range… (More)
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Highly Cited
2001
Highly Cited
2001
Rituximab is a chimeric monoclonal antibody that targets B-cell-specific antigen CD20 and an effective treatment for B-cell non… (More)
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Highly Cited
1994
Highly Cited
1994
The serious shortage of human organs available for transplantation has engendered a heightened interest in the use of animal… (More)
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Highly Cited
1993
Highly Cited
1993
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired stem-cell disorder in which the glycolipid-anchored membrane proteins… (More)
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