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Complement Inactivating Agents

Known as: Complement Inhibitors, complement inhibitor, Inhibiting Agents, Complement 
Compounds that negatively regulate the cascade process of COMPLEMENT ACTIVATION. Uncontrolled complement activation and resulting cell lysis is… 
National Institutes of Health

Related topics

Related topics

22 relations

Narrower (13)

C1 esterase inhibitorC4bp complement proteinC5a peptidaseCD59 Antigen
Complement ActivationComplement Inhibitor [EPC]Immunosuppressive AgentsIn Blood

Broader (1)

antagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Tongue sole (Cynoglossus semilaevis) CD59: A complement inhibitor that binds bacterial cells and promotes bacterial escape from the killing of fish serum.
2010
2010
Novel Adenovirus Vectors ‘Capsid-Displaying’ a Human Complement Inhibitor
Adenovirus (Ad) vectors are currently the most commonly utilized gene transfer vectors in humans worldwide. Unfortunately, upon… 
2009
2009
Characterization of the Complement Inhibitory Function of Rhesus Rhadinovirus Complement Control Protein (RCP)*
Rhesus rhadinovirus (RRV) is currently the closest known, fully sequenced homolog of human Kaposi sarcoma-associated herpesvirus… 
Highly Cited
2003
Highly Cited
2003
Association Between Complement Factor H and Proteoglycans in Early Human Coronary Atherosclerotic Lesions: Implications for Local Regulation of Complement Activation
Objective—Complement activation has been suggested to play a role in atherogenesis. To study the regulation of complement… 
2001
2001
Expression of a soluble complement inhibitor protects transgenic mice from antibody-induced acute renal failure.
Crry is a potent complement regulator in rodents that inhibits C3 convertases. In rats, intrarenal arterial injection of anti… 
1996
1996
Role of a disulfide-bonded peptide loop within human complement C9 in the species-selectivity of complement inhibitor CD59.
CD59 antigen is a membrane glycoprotein that inhibits the activity of the C9 component of the C5b-9 membrane attack complex (MAC… 
Highly Cited
1995
Highly Cited
1995
Exogenous glycosyl phosphatidylinositol-anchored CD59 associates with kinases in membrane clusters on U937 cells and becomes Ca(2+)-signaling competent
CD59, an 18-20-kD complement inhibitor anchored to the membrane via glycosyl phosphatidylinositol (GPI), can induce activation of… 
1995
1995
Characterization of a glycosyl-phosphatidylinositol anchor-deficient subline of Raji cells. An analysis of the functional importance of complement inhibitors on the Raji cell line.
Analysis of complement inhibitory proteins present on the surface of Raji cells (obtained from the European Collection of Animal… 
Highly Cited
1994
Highly Cited
1994
Inhibition of complement-mediated cytolysis by the terminal complement inhibitor of herpesvirus saimiri
Herpesvirus saimiri (HVS) is a lymphotropic herpesvirus that induces T-cell transformation in vitro and causes lymphomas and… 
Highly Cited
1993
Highly Cited
1993
Expression of messenger RNAs for complement inhibitors in human tissues and tumors.
The mRNAs coding for three complement inhibitors produced by human cells, complement cytolysis inhibitor (CLI), decay… 
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