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Complement Inactivating Agents
Known as:
Complement Inhibitors
, complement inhibitor
, Inhibiting Agents, Complement
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Compounds that negatively regulate the cascade process of COMPLEMENT ACTIVATION. Uncontrolled complement activation and resulting cell lysis is…
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National Institutes of Health
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Related topics
Related topics
22 relations
Narrower (13)
C1 esterase inhibitor
C4bp complement protein
C5a peptidase
CD59 Antigen
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Complement Activation
Complement Inhibitor [EPC]
Immunosuppressive Agents
In Blood
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Broader (1)
antagonists & inhibitors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Species specificity of the complement inhibitor compstatin investigated by all‐atom molecular dynamics simulations
P. Tamamis
,
D. Morikis
,
C. Floudas
,
G. Archontis
Proteins: Structure, Function, and Bioinformatics
2010
Corpus ID: 16360793
The development of compounds to regulate the activation of the complement system in non‐primate species is of profound interest…
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2009
2009
Characterization of the Complement Inhibitory Function of Rhesus Rhadinovirus Complement Control Protein (RCP)*
M. Okrój
,
L. Mark
,
+6 authors
A. Blom
Journal of Biological Chemistry
2009
Corpus ID: 24195071
Rhesus rhadinovirus (RRV) is currently the closest known, fully sequenced homolog of human Kaposi sarcoma-associated herpesvirus…
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2004
2004
Production of a complement inhibitor possessing sialyl Lewis X moieties by in vitro glycosylation technology.
L. Thomas
,
K. Panneerselvam
,
+9 authors
R. Bayer
Glycobiology
2004
Corpus ID: 9766291
Recombinant soluble human complement receptor type 1 (sCR1) is a highly glycosylated glycoprotein intended for use as a drug to…
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Highly Cited
2003
Highly Cited
2003
Association Between Complement Factor H and Proteoglycans in Early Human Coronary Atherosclerotic Lesions: Implications for Local Regulation of Complement Activation
R. Oksjoki
,
H. Jarva
,
P. Kovanen
,
Petri Laine
,
S. Meri
,
M. Pentikäinen
Arteriosclerosis, Thrombosis and Vascular Biology
2003
Corpus ID: 28947094
Objective—Complement activation has been suggested to play a role in atherogenesis. To study the regulation of complement…
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2003
2003
Prevention of Collagen-Induced Arthritis in Mice Transgenic for the Complement Inhibitor Complement Receptor 1-Related Gene/Protein y1
N. Banda
,
Damian M. Kraus
,
M. Muggli
,
A. Bendele
,
V. Holers
,
W. Arend
Journal of Immunology
2003
Corpus ID: 8852525
The objective of these studies was to examine collagen-induced arthritis (CIA) in C57BL/6 mice transgenic for the rodent…
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1996
1996
Role of a disulfide-bonded peptide loop within human complement C9 in the species-selectivity of complement inhibitor CD59.
T. Husler
,
D. H. Lockert
,
P. Sims
Biochemistry
1996
Corpus ID: 23549243
CD59 antigen is a membrane glycoprotein that inhibits the activity of the C9 component of the C5b-9 membrane attack complex (MAC…
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Highly Cited
1995
Highly Cited
1995
Exogenous glycosyl phosphatidylinositol-anchored CD59 associates with kinases in membrane clusters on U937 cells and becomes Ca(2+)-signaling competent
Carmen W Van Den Berg
,
T. Cinek
,
M. B. Hallett
,
Vaclav Horejsi
,
B. Morgan
,
P. Morgan
Journal of Cell Biology
1995
Corpus ID: 15284443
CD59, an 18-20-kD complement inhibitor anchored to the membrane via glycosyl phosphatidylinositol (GPI), can induce activation of…
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Highly Cited
1994
Highly Cited
1994
Inhibition of complement-mediated cytolysis by the terminal complement inhibitor of herpesvirus saimiri
R. Rother
,
Scott A. Rollins
,
+4 authors
S. Squinto
Journal of Virology
1994
Corpus ID: 22943069
Herpesvirus saimiri (HVS) is a lymphotropic herpesvirus that induces T-cell transformation in vitro and causes lymphomas and…
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1993
1993
HIV‐I and HIV‐2 isolates differ in their ability to activate the complement system on the surface of infected cells
P. Marschang
,
L. Gurtler
,
+5 authors
M. Dierich
AIDS (London)
1993
Corpus ID: 42132483
OBJECTIVE To analyse the ability of different HIV-1 and HIV-2 isolates to activate the complement system. DESIGN H9 cells…
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Highly Cited
1993
Highly Cited
1993
Expression of messenger RNAs for complement inhibitors in human tissues and tumors.
Sanjay Kumar
,
J. M. Vinci
,
B. Pytel
,
C. Baglioni
Cancer Research
1993
Corpus ID: 25860771
The mRNAs coding for three complement inhibitors produced by human cells, complement cytolysis inhibitor (CLI), decay…
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