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Complement Activation

Known as: activation complement, Activations, Complement, complement pathway regulation 
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal… 
National Institutes of Health

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AntigensC1QA geneC1QA wt AlleleC2 wt Allele

Broader (3)

Complement-Dependent CytotoxicityImmune responsecomplement pathway

Papers overview

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1994
1994
Role of antibody synthesis and complement activation in concordant xenograft retransplantation.
A mouse-to-rat heart retransplantation model was used to study the effects of complement depletion and antibody production with… 
1987
1987
Effect of dialyzer reprocessing methods on complement activation and hemodialyzer-related symptoms.
The effects of different dialyzer processing methods and of reuse on complement activation and dialyzer-related symptoms were… 
1987
1987
Decay-accelerating factor (DAF) shares a common carbohydrate determinant with the variant surface glycoprotein (VSG) of the African Trypanosoma brucei.
Decay-accelerating factor (DAF) is an integral membrane protein that inhibits amplification of the complement cascade on the cell… 
1986
1986
Complement activation in human lymph: modulation by the contact activation system and by leukocytes.
Complement components, their activation and the generation of C3a and C5a peptides were studied in human lymph used as a model of… 
Highly Cited
1984
Highly Cited
1984
Increased expression of the C3b receptor by neutrophils and complement activation during haemodialysis.
Activation of complement and the relative number of C3b receptors expressed by neutrophils was assessed in patients undergoing… 
1981
1981
Activated factor B (Bb) of the alternative pathway of complement activation cleaves and activates plasminogen.
Activated Factor B (Bb), the central serine esterase of the alternative pathway of complement activation, exhibits restricted… 
1981
1981
The in vitro activation of complement by radiologic contrast materials and its inhibition with epsilon-aminocaproic acid.
Radiologic contrast materials activate complement by both the classical and alternative pathways. This activation is time, dose… 
1981
1981
A fluorescent assay for complement activation.
We report here a rapid assay for the complement enzymes CVFBb, C4b2a and Cls. This assay involves the use of a peptide substrate… 
1979
1979
Effect of anti-P1A1 antibody on human platelets. I. The role of complement.
We studied the interaction of complement with human platelets. Complement was activated by IgG anti-P1A1 antibody obtained from 3… 
Highly Cited
1972
Highly Cited
1972
C1r deficiency: an inborn error associated with cutaneous and renal disease.
The studies of sera from two siblings with C1r deficiency are described. The brother (18 yr old) has shown clinical…