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Complement Activation

Known as: activation complement, Activations, Complement, complement pathway regulation 
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal… 
National Institutes of Health

Related topics

Related topics

49 relations
AntigensC1QA geneC1QA wt AlleleC2 wt Allele

Broader (3)

Complement-Dependent CytotoxicityImmune responsecomplement pathway

Papers overview

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Highly Cited
2004
Highly Cited
2004
Demonstration of the Involvement of Outer Surface Protein E Coiled Coil Structural Domains and Higher Order Structural Elements in the Binding of Infection-Induced Antibody and the Complement…
Factor H (fH) is an important regulator of the alternative complement cascade. Several human pathogens have been shown to bind fH… 
Highly Cited
2003
Highly Cited
2003
Association Between Complement Factor H and Proteoglycans in Early Human Coronary Atherosclerotic Lesions: Implications for Local Regulation of Complement Activation
Objective—Complement activation has been suggested to play a role in atherogenesis. To study the regulation of complement… 
Highly Cited
2000
Highly Cited
2000
Acute vascular rejection is associated with systemic complement activation ina pig‐to‐primate kidney xenograft model
Abstract: The introduction of h‐DAF transgenic porcine organs into pre‐clinical pig‐to‐primate discordant xenotransplantation has… 
Highly Cited
1997
Highly Cited
1997
Ancient origin of the complement lectin pathway revealed by molecular cloning of mannan binding protein-associated serine protease from a urochordate, the Japanese ascidian, Halocynthia roretzi.
Recent identification of a C3-like gene in sea urchins revealed the presence of a complement system in invertebrates. To… 
1988
1988
Structure of the murine complement factor H gene.
Highly Cited
1987
Highly Cited
1987
Complement activation by hydroxyethylmethacrylate-ethylmethacrylate copolymers.
Certain biomaterials, including nylon oxygenator and cellulosic dialysis membranes, are potent activators of human complement. In… 
Highly Cited
1986
Highly Cited
1986
Complement activation in rheumatoid arthritis evaluated by C3dg and the terminal complement complex.
Complement activation was evaluated in plasma and synovial fluid from patients with rheumatoid arthritis. The activation fragment… 
Highly Cited
1976
Highly Cited
1976
In vitro synthesis of factor B of the alternative pathway of complement activation by mouse peritoneal macrophages
Factor B of the alternative pathway of complement activation was shown to be synthesized and secreted by unstimulated mouse… 
Highly Cited
1973
Highly Cited
1973
Consumption of human complement components by complexes of IgG with protein A of Staphylococcus aureus.
Highly Cited
1971
Highly Cited
1971
Cell cycle-dependent immune lysis of Moloney virus-transformed lymphocytes: presence of viral antigen, accessibility to antibody, and complement activation.
The expression of Moloney leukemia virus on the surface of a viral-induced lymphoma cell, availability of the virus to anti-viral… 
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