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Complement-Dependent Cytotoxicity

Activated by cell-surface bound antibody, by immune complexes, or by microbial membrane carbohydrate, Complement-Dependent Cytotoxicity involves… 
National Institutes of Health

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AntigensComplement dependent cytotoxicityImmunityapolizumab

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Complement Activation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Mutations of Recombinant Aquaporin-4 Antibody in the Fc Domain Can Impair Complement-Dependent Cellular Cytotoxicity and Transplacental Transport
Maternal antibodies provide protection for the developing fetus. Transplacental transport of pathogenic autoantibodies might pose… 
1987
1987
Role of cellular and humoral immunity and helper cell involvement in permissiveness to infection by Schistosoma mansoni
Cellular and humoral parameters were studied in permissive (mouse) and nonpermissive (rat) animals during the first few weeks… 
1987
1987
Enrichment of human marrow T-cell precursors by complement-dependent cytotoxicity with monoclonal antibodies and Percoll Gradient centrifugation.
Attempts to enrich and characterize human marrow T-cell precursors have been performed using discontinuous Percoll gradient… 
1986
1986
IgM antibodies recognizing carbohydrate epitopes shared between schistosomula and miracidia of Schistosoma mansoni that block in vitro killing.
A series of monoclonal antibodies (mAb) was raised in mice against Schistosoma mansoni, which recognized a carbohydrate… 
1985
1985
Murine tumor cell lysis by antibody-dependent macrophage-mediated cytotoxicity using syngeneic monoclonal antibodies.
Four monoclonal antibodies to MH134 murine syngeneic hepatoma cells, 3H1, 7C2, 11G2, and 12A2, were produced by hybridomas… 
1983
1983
Differential antigenic expression of the DBA/2 lymphoma L1210 and its sublines: cross-reactivity with C3H mammary tumors as defined by syngeneic monoclonal antibodies.
The expression of tumor-associated antigens on the DBA/2 lymphoma L1210 and three L1210 sublines, each resistant to a different… 
Highly Cited
1981
Highly Cited
1981
Clonal variation in expression of a human melanoma antigen defined by a monoclonal antibody.
Previous work established 3 monoclonal mouse antibodies, 3.1, 3.2, and 3.3, which define an antigenic determinant that is… 
Highly Cited
1980
Highly Cited
1980
Serological and immunochemical characterization of monoclonal antibodies to Toxoplasma gondii.
The fusion of mouse NS-1 myeloma cells with spleen cells from mice chronically infected with Toxoplasma gondii resulted in eight… 
1979
1979
Neural cell sequestration on immunoaffinity columns.
1976
1976
Tumor-bound immunoglobulins: an in vivo phenomenon of masked specificity.
We examined the specificity of the lg "coating" on murine tumor cells grown in vivo. Cells were treated in vitro for release of… 
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