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Complement dependent cytotoxicity

Known as: CDC 
National Institutes of Health

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Complement-Dependent Cytotoxicity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Recombinant human IgG1 based Fc multimers, with limited FcR binding capacity, can effectively inhibit complement-mediated disease.
2016
2016
Glycyrrhizic acid prevents astrocyte death by neuromyelitis optica-specific IgG via inhibition of C1q binding.
2013
2013
CD20 mAb-Mediated Complement Dependent Cytotoxicity of Tumor Cells is Enhanced by Blocking the Action of Factor I
The CD20 mAbs, rituximab (RTX) and ofatumumab (OFA), have been used with success in the clinic in the treatment of B cell… 
2008
2008
Binding of Submaximal C1q to B Cells Opsonized with Anti-CD20 Mabs Ofatumumab (OFA) or Rituximab (RTX) Promotes Complement Dependent Cytotoxicity (CDC), and Considerably Higher Levels of CDC Are…
The CD20 mAb OFA is more effective than RTX in promoting lysis of opsonized B cells via classical pathway CDC, likely due to the… 
2008
2008
Resistance to anti-xenogeneic response by combining alpha-Gal silencing with HO-1 upregulation.
2006
2006
Heart transplantation across antibodies against human leukocyte antigens and blood group A1 antigen. Post‐transplant follow‐up of donor reactive antibodies
Abstract: Background: We have successfully performed heart transplantation despite the most unfavourable risk factors for graft… 
Review
2006
Review
2006
Antibodies and their fragments as anti-cancer agents.
The recent developments in the field of recombinant DNA, protein engineering and cancer biology, have let us gain insight into… 
1991
1991
Autoreactive lymphocytotoxic IgM antibodies in highly sensitized dialysis patients waiting for a kidney transplant: identification and clinical relevance.
The contribution of different families of lymphocytotoxic antibodies in the serologic reactivity of 45 highly sensitized dialysis… 
1990
1990
Antibody dependent cellular cytotoxicity and complement mediated cytotoxicity on leukemic cells mediated by anti K562 monoclonal antibodies.
Three anti K562 monoclonal antibodies (MAb) 4.3, 4.6 and 4.8 reacting predominantly with cells of myeloid lineage, were tested… 
1979
1979
Antibody dependent cell mediated cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC) in 229 sera from human renal allograft recipients.
Comparison between CDC and ADCC in a human allogeneic model using the same cytotoxicity marker, i.e. 51Cr release from labelled… 
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