Complement dependent cytotoxicity

Known as: CDC 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2016
02419792016

Papers overview

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2015
2015
Many therapeutic antibodies have been developed, and IgG antibodies have been extensively generated in various cell expression… (More)
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2012
2012
Complement dependent cytotoxicity (CDC) is an important mechanism of action for monoclonal antibodies (mAbs) used in the… (More)
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Highly Cited
2011
Highly Cited
2011
Serum autoantibodies against the water channel aquaporin-4 (AQP4) are important diagnostic biomarkers and pathogenic factors for… (More)
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2008
2008
The mechanism of cytotoxicity of alemtuzumab and rituximab in chronic lymphocytic leukemia (CLL) is not well understood. We… (More)
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Highly Cited
2007
Highly Cited
2007
The standard method to detect pretransplant antibodies has been the complement dependent cytotoxicity (CDC) test of donor… (More)
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2004
2004
Metastases from renal cell carcinomas (RCC) are resistant to radiation and chemotherapy but are relatively immunogenic. We have… (More)
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2002
2002
BACKGROUND In many situations, anti-CD154 (CD40 ligand) monoclonal antibody (mAb) treatment is very potent in producing allograft… (More)
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2001
2001
OBJECTIVE To study complement and cell mediated cytotoxicity by antiendothelial cell antibodies (AECA) in Takayasu's arteritis… (More)
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1997
1997
BACKGROUND One reason for the failure of monoclonal antibody (mab) trials in most cancer patients might be the presence of… (More)
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1979
1979
Comparison between CDC and ADCC in a human allogeneic model using the same cytotoxicity marker, i.e. 51Cr release from labelled… (More)
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