Fixing , Luminex Binding Antibodies — A New Tool for Prediction of Graft Failure After Heart Transplantation

@inproceedings{Smitha2007FixingL,
  title={Fixing , Luminex Binding Antibodies — A New Tool for Prediction of Graft Failure After Heart Transplantation},
  author={J. D. Smitha and I. M. Hamourb and N. R. Bannerb and M. L. Rosea},
  year={2007}
}
  • J. D. Smitha, I. M. Hamourb, +1 author M. L. Rosea
  • Published 2007
The standard method to detect pretransplant antibodies has been the complement dependent cytotoxicity (CDC) test of donor leukocytes. Solid phase assays to detect HLA antibodies in pretransplant serum reveal a greater number of sensitized patients, but their clinical impact is less certain. Here we have developed a method of detecting C4d fixing HLA antibodies on Luminex beads. Pretransplant serum from 565 cardiac transplant patients was retrospectively tested for the presence of HLA antibodies… CONTINUE READING