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apolizumab
Known as:
Monoclonal Antibody Hu1D10
, MOAB Hu1D10
, Monoclonal antibody 1D10
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A humanized monoclonal antibody directed against 1D10, a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic…
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National Institutes of Health
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Related topics
Related topics
10 relations
Broader (2)
Antibodies, Monoclonal, Humanized
Monoclonal Antibodies
Antibody-Dependent Cellular Cytotoxicity
B-Lymphocytes
Complement-Dependent Cytotoxicity
HLA-DR Antigens
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Narrower (2)
Hu1D 10
Remitogen
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Blockade of CD47-Sirpα Interactions Improved Myeloid Effector Cell Mediated Lymphoma Cell Killing By the HLA-DR Antibody Apolizumab
J. Petersen
,
T. Rösner
,
+7 authors
T. Valerius
Blood
2019
Corpus ID: 209239456
Background:Apolizumab (APO) is a humanized IgG1 antibody targeting a HLA-DRβ chain specific epitope, which is expressed by approx…
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2008
2008
Caracterização funcional do anticorpo monoclonal humano BH1
Dianne Marie Barroso Catalão
2008
Corpus ID: 191973156
Embora, existam novas terapias e avancos no tratamento do cancro, por vezes, os beneficios esperados nao sao alcancados. O drama…
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2005
2005
In Vitro Activity of the Humanized Anti-HLA-DR Antibodies KRN848 and Apolizumab in Non-Hodgkins Lymphoma Cell Lines.
M. Hill
,
G. Weiner
,
B. Link
2005
Corpus ID: 78879405
Apolizumab (Hu1D10) and KRN848 are humanized IgG1 anti-HLA-DR monoclonal antibodies (mAb). Apolizumab binds a polymorphic…
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2005
2005
A Humanized HLA-DR Antibody (HU1D10, Apolizumab) in Combination with G-CSF (Filgrastim) for the Treatment of Non-Hodgkin’s Lymphoma: A Pilot Study.
J. Rech
,
R. Repp
,
+7 authors
T. Valerius
2005
Corpus ID: 78717783
Apolizumab is a humanized monoclonal antibody against a polymorhic epitope on HLA DRs, which demonstrated evidence for…
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2004
2004
Hu 1 D 10 induces apoptosis concurrent with activation of the AKT survival pathway in human chronic lymphocytic leukemia cells
A. Mone
,
Peng Huang
,
+7 authors
J. Byrd
2004
Corpus ID: 27573834
The 1D10 antigen is the target for Hu1D10 (apolizumab), a humanized HLA-DR -chain–specific antibody that is currently in clinical…
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Review
2004
Review
2004
Novel therapies for chronic lymphocytic leukemia.
B. Mavromatis
,
B. Cheson
Blood reviews
2004
Corpus ID: 30062904
Highly Cited
2004
Highly Cited
2004
Hu1D10 induces apoptosis concurrent with activation of the AKT survival pathway in human chronic lymphocytic leukemia cells.
A. Mone
,
Peng Huang
,
+7 authors
J. Byrd
Blood
2004
Corpus ID: 206862257
The 1D10 antigen is the target for Hu1D10 (apolizumab), a humanized HLA-DR beta-chain-specific antibody that is currently in…
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2003
2003
Gateways to clinical trials.
M. Bayés
,
X. Rabasseda
,
J. Prous
Methods and Findings in Experimental and Clinical…
2003
Corpus ID: 27013008
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the…
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2003
2003
Gateways to clinical trials.
M. Bayés
,
X. Rabasseda
,
J. Prous
Methods and Findings in Experimental and Clinical…
2003
Corpus ID: 12836253
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the…
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2002
2002
Immunotherapy of non-Hodgkin's lymphoma with hLL2 (epratuzumab, an anti-CD22 monoclonal antibody) and Hu1D10 (apolizumab).
J. Leonard
,
B. Link
Seminars in Oncology
2002
Corpus ID: 21874132
Clinical activity of anti-CD20 monoclonal antibodies both in the unlabeled (rituximab [Rituxan; Genentech, Inc, South San…
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