Monoclonal Antibodies

Known as: Antibodies, Monoclonal, Monoclonal Antibody, MAb 
A type of protein made in the laboratory that can bind to substances in the body, including tumor cells. There are many kinds of monoclonal… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2019
02000400019712019

Related topics

Related topics

49 relations
1 ML palivizumab 100 MG/ML Injectionpalivizumabpembrolizumab

Narrower (44)

2G12 monoclonal antibodyABT-874 antibody, humanALXN4100AMG 479
(More)

Broader (2)

AntibodiesImmunologic Factors

Related mentions per year

Related mentions per year

1937-2019
19401960198020002020
Monoclonal Antibodies
rituximab
Antibodies
Immunologic Factors
abciximab
pembrolizumab

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Second- and third-generation drugs for immuno-oncology treatment-The more the better?
Recent success in cancer immunotherapy (anti-CTLA-4, anti-PD1/PD-L1) has confirmed the hypothesis that the immune system can… (More)
Is this relevant?
Review
2017
Review
2017
Journey of TRAIL from Bench to Bedside and its Potential Role in Immuno-Oncology
Induction of apoptosis in cancer cells has increasingly been the focus of many therapeutic approaches in oncology field. Since… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • table 3
Is this relevant?
Review
2016
Review
2016
Daratumumab: a first-in-class CD38 monoclonal antibody for the treatment of multiple myeloma
Daratumumab is a human monoclonal antibody that targets CD38, a cell surface protein that is overexpressed on multiple myeloma… (More)
  • figure 1
  • table 1
  • table 2
Is this relevant?
Review
2016
Review
2016
Toxicity management of immunotherapy for patients with metastatic melanoma.
Checkpoint inhibitors have revolutionized the treatment of patients with metastatic melanoma offering improved responses and… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for…
PURPOSE Overexpression of the HER2 protein occurs in 25% to 30% of human breast cancers and leads to a particularly aggressive… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.
PURPOSE The CD20 antigen is expressed on more than 90% of B-cell lymphomas. It is appealing for targeted therapy, because it does… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.
BACKGROUND Studies in animals and an open-label trial have suggested a role for antibodies to tumor necrosis factor alpha… (More)
Is this relevant?
Highly Cited
1985
Highly Cited
1985
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.
Six monoclonal antibodies have been isolated from mice immunized with synthetic peptide immunogens whose sequences are derived… (More)
Is this relevant?
Highly Cited
1984
Highly Cited
1984
Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).
A murine monoclonal antibody specific for calf intestinal alkaline phosphatase has been prepared and used in an unlabeled… (More)
Is this relevant?
Highly Cited
1984
Highly Cited
1984
Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.
The monoclonal antibody Ki-67 detects a nuclear antigen that is present only in proliferating cells. The aim of the present… (More)
Is this relevant?