Monoclonal Antibodies

Known as: Antibodies, Monoclonal, Monoclonal Antibody, MAb 
A type of protein made in the laboratory that can bind to substances in the body, including tumor cells. There are many kinds of monoclonal… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2019
02000400019712019

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Recent success in cancer immunotherapy (anti-CTLA-4, anti-PD1/PD-L1) has confirmed the hypothesis that the immune system can… (More)
Is this relevant?
Review
2017
Review
2017
Induction of apoptosis in cancer cells has increasingly been the focus of many therapeutic approaches in oncology field. Since… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • table 3
Is this relevant?
Review
2016
Review
2016
Daratumumab is a human monoclonal antibody that targets CD38, a cell surface protein that is overexpressed on multiple myeloma… (More)
  • figure 1
  • table 1
  • table 2
Is this relevant?
Review
2016
Review
2016
Checkpoint inhibitors have revolutionized the treatment of patients with metastatic melanoma offering improved responses and… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
PURPOSE Overexpression of the HER2 protein occurs in 25% to 30% of human breast cancers and leads to a particularly aggressive… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
PURPOSE The CD20 antigen is expressed on more than 90% of B-cell lymphomas. It is appealing for targeted therapy, because it does… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
BACKGROUND Studies in animals and an open-label trial have suggested a role for antibodies to tumor necrosis factor alpha… (More)
Is this relevant?
Highly Cited
1985
Highly Cited
1985
Six monoclonal antibodies have been isolated from mice immunized with synthetic peptide immunogens whose sequences are derived… (More)
Is this relevant?
Highly Cited
1984
Highly Cited
1984
A murine monoclonal antibody specific for calf intestinal alkaline phosphatase has been prepared and used in an unlabeled… (More)
Is this relevant?
Highly Cited
1984
Highly Cited
1984
The monoclonal antibody Ki-67 detects a nuclear antigen that is present only in proliferating cells. The aim of the present… (More)
Is this relevant?