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Monoclonal Antibodies

Known as: Antibodies, Monoclonal, Monoclonal Antibody, MAb 
A type of protein made in the laboratory that can bind to substances in the body, including tumor cells. There are many kinds of monoclonal… 
National Institutes of Health

Related topics

Related topics

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0.8 ML adalimumab 50 MG/ML Prefilled Syringe1 ML palivizumab 100 MG/ML Injectionevolocumabpalivizumab

Narrower (43)

2G12 monoclonal antibodyABT-874 antibody, humanALXN4100AMG 479

Broader (2)

AntibodiesImmunologic Factors

Papers overview

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Highly Cited
2013
Highly Cited
2013
Therapeutic Efficacy of Potent Neutralizing HIV-1-Specific Monoclonal Antibodies in SHIV-Infected Rhesus Monkeys
Human immunodeficiency virus type 1 (HIV-1)-specific monoclonal antibodies with extraordinary potency and breadth have recently… 
Highly Cited
2012
Highly Cited
2012
Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis.
BACKGROUND Type 17 helper T cells have been suggested to play a pathological role in psoriasis. They secrete several… 
Highly Cited
2009
Highly Cited
2009
PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies.
The monoclonal antibodies (moAb) panitumumab and cetuximab target the epidermal growth factor receptor (EGFR) and have proven… 
Highly Cited
2008
Highly Cited
2008
Use of Ly6G‐specific monoclonal antibody to deplete neutrophils in mice
The anti‐granulocyte receptor‐1 (Gr‐1) mAb, RB6‐8C5, has been used extensively to deplete neutrophils in mice and to investigate… 
Highly Cited
2006
Highly Cited
2006
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412.
Six healthy young male volunteers at a contract research organization were enrolled in the first phase 1 clinical trial of… 
Highly Cited
2004
Highly Cited
2004
Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate
Purpose: An antibody-drug conjugate consisting of monomethyl auristatin E (MMAE) conjugated to the anti-CD30 monoclonal antibody… 
Highly Cited
1993
Highly Cited
1993
Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha.
OBJECTIVE To evaluate the safety and efficacy of a chimeric monoclonal antibody to tumor necrosis factor alpha (TNF alpha) in the… 
Highly Cited
1987
Highly Cited
1987
Identification of a monoclonal antibody specific for a murine T3 polypeptide.
A monoclonal antibody (145-2C11) specific for the murine T3 complex was derived by immunizing Armenian hamsters with a murine… 
Highly Cited
1984
Highly Cited
1984
Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells.
The anti-My-10 mouse monoclonal antibody was raised against the immature human myeloid cell line KG-1a and was selected for… 
Highly Cited
1983
Highly Cited
1983
A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer.
The murine monoclonal antibody OC 125 reacts with an antigen (CA 125) common to most nonmucinous epithelial ovarian carcinomas… 
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