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HLA-DR Antigens

Known as: human histocompatibility complex derived antigens-DR Antigen, HLA-DR Ag, HLA-DR Antigen 
Encoded by multiple HLA-DRA and HLA-DRB genes in a complex variable 5 cM region of MHC between HLA-B and -D, HLA-DR Antigens are Class II… 
National Institutes of Health

Related topics

Related topics

26 relations
Antigen PresentationCD4 Positive T LymphocytesCytoplasmic DomainGenes, MHC Class II

Broader (2)

HLA-D AntigensHistocompatibility Antigens Class II

Narrower (2)

HLA-DR53XM1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Tumor-Infiltrating Lymphocytes Expressing the Tissue Resident Memory Marker CD103 Are Associated with Increased Survival in High-Grade Serous Ovarian Cancer
Background: The presence of CD8+ tumor-infiltrating lymphocytes (TIL) is associated with prolonged survival in high-grade serous… 
Highly Cited
1999
Highly Cited
1999
Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices
Most pockets in the human leukocyte antigen–group DR (HLA-DR) groove are shaped by clusters of polymorphic residues and, thus… 
Highly Cited
1998
Highly Cited
1998
Persistent allopeptide reactivity and epitope spreading in chronic rejection of organ allografts.
The role of the indirect allorecognition pathway in acute allograft rejection has been documented both in organ recipients and in… 
Highly Cited
1997
Highly Cited
1997
Constraints on CD4 recovery postchemotherapy in adults: thymic insufficiency and apoptotic decline of expanded peripheral CD4 cells.
To examine the mechanisms of CD4 reconstitution in an adult population, lymphocyte repopulation was assessed following dose… 
Highly Cited
1990
Highly Cited
1990
Monocyte HLA‐DR antigen expression characterizes clinical outcome in the trauma patient
Immunological assessment is important to characterize the host defence response of trauma patients as infection is the most… 
Highly Cited
1986
Highly Cited
1986
Polymorphism of human Ia antigens: gene conversion between two DR β loci results in a new HLA-D/DR specificity
The polymorphic HLA-DR β-chains are encoded within the human major histocompatibility complex (MHC) by multiple loci resulting… 
Highly Cited
1985
Highly Cited
1985
Interferon-gamma induces HLA-DR expression by thyroid epithelium.
We recently showed that human thyroid epithelial cells, which are normally negative for HLA-DR molecules, express HLA-DR in… 
Highly Cited
1983
Highly Cited
1983
HLA-D region β-chain DNA endonuclease fragments differ between HLA-DR identical healthy and insulin-dependent diabetic individuals
The human HLA-D histocompatibility region encodes class II antigens each of which consists of two polypeptide chains (α and… 
Highly Cited
1982
Highly Cited
1982
Possible involvement of the OKT4 molecule in T cell recognition of class II HLA antigens. Evidence from studies of cytotoxic T lymphocytes specific for SB antigens
A recently described HLA gene, SB, which maps between GLO and HLA-DR, codes for Ia-like molecules that are similar to but… 
Highly Cited
1980
Highly Cited
1980
Evidence for a new segregant series of B cell antigens that are encoded in the HLA-D region and that stimulate secondary allogenic proliferative and cytotoxic responses
Five new histocompatibility antigens, designated secondary B cell or (SB) antigens, have been identified by secondary allogeneic… 
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