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Histocompatibility Antigens Class II

Known as: Antigens, Class II, Antigens, Immune-Response-Associated, Human Leukocyte Antigen 
Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural… 
National Institutes of Health

Related topics

Related topics

38 relations
Antigen PresentationAntigen-Presenting CellsCD4 Positive T LymphocytesGenes, MHC Class II

Narrower (19)

BoDr-betaII antigenBoLA-DQA antigenBoLA-DQB antigenBoLA-DRB3 antigen

Broader (1)

Histocompatibility Antigens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid
Exosomes are 30–100 nm diameter vesicles formed by inward budding of endosomal compartments and are produced by several cell… 
Highly Cited
2001
Highly Cited
2001
Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells
Immature dendritic cells (DCs) sample their environment for antigens and after stimulation present peptide associated with major… 
Highly Cited
2000
Highly Cited
2000
The Formation of Immunogenic Major Histocompatibility Complex Class II–Peptide Ligands in Lysosomal Compartments of Dendritic Cells Is Regulated by Inflammatory Stimuli
During their final differentiation or maturation, dendritic cells (DCs) redistribute their major histocompatibility complex (MHC… 
Highly Cited
1999
Highly Cited
1999
Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices
Most pockets in the human leukocyte antigen–group DR (HLA-DR) groove are shaped by clusters of polymorphic residues and, thus… 
Review
1992
Review
1992
Immunological aspects of demyelinating diseases.
Primary demyelination in the central nervous system results from damage to the myelin sheath or oligodendroglia and can be… 
Highly Cited
1991
Highly Cited
1991
Identification of self peptides bound to purified HLA-B27
A pool of endogenous peptides bound to the human class I MHC molecule, HLA-B27, has been isolated. Microsequence analysis of the… 
Highly Cited
1989
Highly Cited
1989
Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection.
To study the mechanism of maintenance of polymorphism at major histocompatibility complex (MHC) loci, synonymous and… 
Highly Cited
1986
Highly Cited
1986
Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes
Allelic sequence variation has been analysed by synthetic oligonucleotide hybridization probes which can detect single base… 
Highly Cited
1984
Highly Cited
1984
Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts.
Immune interferon (IFN-gamma) increases the surface expression of HLA-A,B antigens and induces the surface expression of HLA-DR… 
Highly Cited
1978
Highly Cited
1978
Association of the B-cell alloantigen DRw4 with rheumatoid arthritis.
Previous testing of patients with rheumatoid arthritis showed that one HLA-D type, Dw4, occurred more frequently than in normal… 
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