Histocompatibility Antigens Class II
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Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and… Expand Major histocompatibility complex (MHC) class II molecules present products of lysosomal proteolysis to CD4(+) T cells. Although… Expand The recent discovery of microRNAs (miRNAs) took many by surprise because of their unorthodox features and widespread functions… Expand Identification and characterization of antigen-specific T lymphocytes during the course of an immune response is tedious and… Expand Presentation of antigenic peptides by MHC class II molecules to CD4+ T cells is critical to the generation of antitumor immunity… Expand An influenza virus peptide binds to HLA-DR1 in an extended conformation with a pronounced twist. Thirty-five per cent of the… Expand CD34+ cells in human cord blood and marrow are known to give rise to dendritic cells (DC), as well as to other myeloid lineages… Expand The three-dimensional structure of the class II histocompatibility glycoprotein HLA-DR1 from human B-cell membranes has been… Expand To study the mechanism of maintenance of polymorphism at major histocompatibility complex (MHC) loci, synonymous and… Expand We detected large numbers of HLA-DR-positive reactive microglia (macrophages), along with Lewy bodies and free melanin, in the… Expand