Histocompatibility Antigens Class II

Known as: Antigens, Class II, Antigens, Immune-Response-Associated, Human Leukocyte Antigen 
Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural… (More)
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Type 1 diabetes (T1D) results from immune-mediated loss of pancreatic beta cells leading to insulin deficiency. It is the most… (More)
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Highly Cited
2010
Highly Cited
2010
Infectious and inflammatory diseases have repeatedly shown strong genetic associations within the major histocompatibility… (More)
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Highly Cited
2007
Highly Cited
2007
Major histocompatibility complex (MHC) class II molecules present products of lysosomal proteolysis to CD4(+) T cells. Although… (More)
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Highly Cited
2000
Highly Cited
2000
Many receptors for endocytosis recycle into and out of cells through early endosomes. We now find in dendritic cells that the DEC… (More)
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Highly Cited
1998
Highly Cited
1998
Cells from the bone marrow can present peptides that are derived from tumors, transplants, and self-tissues. Here we describe how… (More)
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Review
1998
Review
1998
Classical class I molecules assemble in the endoplasmic reticulum (ER) with peptides mostly generated from cytosolic proteins by… (More)
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Highly Cited
1996
Highly Cited
1996
Presentation of antigenic peptides by MHC class II molecules to CD4+ T cells is critical to the generation of antitumor immunity… (More)
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Highly Cited
1996
Highly Cited
1996
Major histocompatibility complex (MHC) genes (HLA in humans) regulate the immune response to foreign antigens. Molecular and… (More)
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Highly Cited
1994
Highly Cited
1994
An influenza virus peptide binds to HLA-DR1 in an extended conformation with a pronounced twist. Thirty-five per cent of the… (More)
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Highly Cited
1993
Highly Cited
1993
The three-dimensional structure of the class II histocompatibility glycoprotein HLA-DR1 from human B-cell membranes has been… (More)
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