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Histocompatibility Antigens Class II

Known as: Antigens, Class II, Antigens, Immune-Response-Associated, Human Leukocyte Antigen 
Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and… Expand
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Highly Cited
2007
Highly Cited
2007
Major histocompatibility complex (MHC) class II molecules present products of lysosomal proteolysis to CD4(+) T cells. Although… Expand
Review
2005
Review
2005
  • V. Kim
  • Nature Reviews Molecular Cell Biology
  • 2005
  • Corpus ID: 11125422
The recent discovery of microRNAs (miRNAs) took many by surprise because of their unorthodox features and widespread functions… Expand
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Highly Cited
1996
Highly Cited
1996
Identification and characterization of antigen-specific T lymphocytes during the course of an immune response is tedious and… Expand
Highly Cited
1996
Highly Cited
1996
Presentation of antigenic peptides by MHC class II molecules to CD4+ T cells is critical to the generation of antitumor immunity… Expand
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Highly Cited
1994
Highly Cited
1994
An influenza virus peptide binds to HLA-DR1 in an extended conformation with a pronounced twist. Thirty-five per cent of the… Expand
Highly Cited
1994
Highly Cited
1994
CD34+ cells in human cord blood and marrow are known to give rise to dendritic cells (DC), as well as to other myeloid lineages… Expand
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Highly Cited
1993
Highly Cited
1993
The three-dimensional structure of the class II histocompatibility glycoprotein HLA-DR1 from human B-cell membranes has been… Expand
Highly Cited
1989
Highly Cited
1989
  • A. Hughes, M. Nei
  • Proceedings of the National Academy of Sciences…
  • 1989
  • Corpus ID: 25810130
To study the mechanism of maintenance of polymorphism at major histocompatibility complex (MHC) loci, synonymous and… Expand
Highly Cited
1988
Highly Cited
1988
We detected large numbers of HLA-DR-positive reactive microglia (macrophages), along with Lewy bodies and free melanin, in the… Expand