Histocompatibility Antigens Class II

Known as: Antigens, Class II, Antigens, Immune-Response-Associated, Human Leukocyte Antigen 
Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural… (More)
National Institutes of Health

Related topics

Related topics

37 relations
Antigen PresentationAntigen-Presenting CellsCD4 Positive T LymphocytesGenes, MHC Class II
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Narrower (18)

BoDr-betaII antigenBoLA-DQA antigenBoLA-DQB antigenBoLA-DRB3 antigen
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Broader (1)

Histocompatibility Antigens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Genetics of type 1 diabetes.
Type 1 diabetes (T1D) results from immune-mediated loss of pancreatic beta cells leading to insulin deficiency. It is the most… (More)
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Highly Cited
2010
Highly Cited
2010
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
Infectious and inflammatory diseases have repeatedly shown strong genetic associations within the major histocompatibility… (More)
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Highly Cited
2007
Highly Cited
2007
Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes.
Major histocompatibility complex (MHC) class II molecules present products of lysosomal proteolysis to CD4(+) T cells. Although… (More)
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Highly Cited
2000
Highly Cited
2000
The Dendritic Cell Receptor for Endocytosis, Dec-205, Can Recycle and Enhance Antigen Presentation via Major Histocompatibility Complex Class II–Positive Lysosomal Compartments
Many receptors for endocytosis recycle into and out of cells through early endosomes. We now find in dendritic cells that the DEC… (More)
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Highly Cited
1998
Highly Cited
1998
Efficient Presentation of Phagocytosed Cellular Fragments on the Major Histocompatibility Complex Class II Products of Dendritic Cells
Cells from the bone marrow can present peptides that are derived from tumors, transplants, and self-tissues. Here we describe how… (More)
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Review
1998
Review
1998
Mechanisms of MHC class I--restricted antigen processing.
Classical class I molecules assemble in the endoplasmic reticulum (ER) with peptides mostly generated from cytosolic proteins by… (More)
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Highly Cited
1996
Highly Cited
1996
Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen.
Presentation of antigenic peptides by MHC class II molecules to CD4+ T cells is critical to the generation of antitumor immunity… (More)
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Highly Cited
1996
Highly Cited
1996
Influence of combinations of human major histocompatibility complex genes on the course of HIV–1 infection
Major histocompatibility complex (MHC) genes (HLA in humans) regulate the immune response to foreign antigens. Molecular and… (More)
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Highly Cited
1994
Highly Cited
1994
Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide
An influenza virus peptide binds to HLA-DR1 in an extended conformation with a pronounced twist. Thirty-five per cent of the… (More)
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Highly Cited
1993
Highly Cited
1993
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
The three-dimensional structure of the class II histocompatibility glycoprotein HLA-DR1 from human B-cell membranes has been… (More)
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