Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Histocompatibility Antigens Class II

Known as: Antigens, Class II, Antigens, Immune-Response-Associated, Human Leukocyte Antigen 
Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural… Expand
National Institutes of Health

Related topics

Related topics

38 relations
Antigen PresentationAntigen-Presenting CellsCD4 Positive T LymphocytesGenes, MHC Class II
Expand

Narrower (19)

BoDr-betaII antigenBoLA-DQA antigenBoLA-DQB antigenBoLA-DRB3 antigen
Expand

Broader (1)

Histocompatibility Antigens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Celiac Disease: A Review of Current Concepts in Pathogenesis, Prevention, and Novel Therapies
Our understanding of celiac disease and how it develops has evolved significantly over the last half century. Although… Expand
  • table 1
  • figure 1
  • figure 2
  • table 2
  • table 3
Is this relevant?
Review
2018
Review
2018
Genetics of immunoglobulin-A vasculitis (Henoch-Schönlein purpura): An updated review.
Immunoglobulin-A vasculitis (IgAV) is classically a childhood small-sized blood vessel vasculitis with predominant involvement of… Expand
  • table 1
  • table 2
Is this relevant?
Review
2018
Review
2018
Genomics of response to immune checkpoint therapies for cancer: implications for precision medicine
Immune checkpoint blockade (ICB) therapies, which potentiate the body’s natural immune response against tumor cells, have shown… Expand
  • figure 1
  • table 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes.
Major histocompatibility complex (MHC) class II molecules present products of lysosomal proteolysis to CD4(+) T cells. Although… Expand
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Phenotypic Analysis of Antigen-Specific T Lymphocytes
Identification and characterization of antigen-specific T lymphocytes during the course of an immune response is tedious and… Expand
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen.
Presentation of antigenic peptides by MHC class II molecules to CD4+ T cells is critical to the generation of antitumor immunity… Expand
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide
An influenza virus peptide binds to HLA-DR1 in an extended conformation with a pronounced twist. Thirty-five per cent of the… Expand
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
The three-dimensional structure of the class II histocompatibility glycoprotein HLA-DR1 from human B-cell membranes has been… Expand
Is this relevant?
Highly Cited
1990
Highly Cited
1990
A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway
MAJOR histocompatibility complex (MHC) class I molecules export peptides to the cell surface for surveillance by cytotoxic T… Expand
Is this relevant?
Highly Cited
1989
Highly Cited
1989
Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection.
  • A. Hughes, M. Nei
  • Proceedings of the National Academy of Sciences…
  • 1989
    • Corpus ID: 25810130
To study the mechanism of maintenance of polymorphism at major histocompatibility complex (MHC) loci, synonymous and… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE