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Histocompatibility Antigens Class II

Known as: Antigens, Class II, Antigens, Immune-Response-Associated, Human Leukocyte Antigen 
Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural… Expand
National Institutes of Health

Related topics

Related topics

38 relations
Antigen PresentationAntigen-Presenting CellsCD4 Positive T LymphocytesGenes, MHC Class II
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Narrower (19)

BoDr-betaII antigenBoLA-DQA antigenBoLA-DQB antigenBoLA-DRB3 antigen
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Broader (1)

Histocompatibility Antigens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and… Expand
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Highly Cited
2007
Highly Cited
2007
Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes.
Major histocompatibility complex (MHC) class II molecules present products of lysosomal proteolysis to CD4(+) T cells. Although… Expand
Review
2005
Review
2005
MicroRNA biogenesis: coordinated cropping and dicing
  • V. Kim
  • Nature Reviews Molecular Cell Biology
  • 2005
    • Corpus ID: 11125422
The recent discovery of microRNAs (miRNAs) took many by surprise because of their unorthodox features and widespread functions… Expand
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Highly Cited
1996
Highly Cited
1996
Phenotypic Analysis of Antigen-Specific T Lymphocytes
Identification and characterization of antigen-specific T lymphocytes during the course of an immune response is tedious and… Expand
Highly Cited
1996
Highly Cited
1996
Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen.
Presentation of antigenic peptides by MHC class II molecules to CD4+ T cells is critical to the generation of antitumor immunity… Expand
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Highly Cited
1994
Highly Cited
1994
Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide
An influenza virus peptide binds to HLA-DR1 in an extended conformation with a pronounced twist. Thirty-five per cent of the… Expand
Highly Cited
1994
Highly Cited
1994
Proliferating dendritic cell progenitors in human blood
CD34+ cells in human cord blood and marrow are known to give rise to dendritic cells (DC), as well as to other myeloid lineages… Expand
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Highly Cited
1993
Highly Cited
1993
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
The three-dimensional structure of the class II histocompatibility glycoprotein HLA-DR1 from human B-cell membranes has been… Expand
Highly Cited
1989
Highly Cited
1989
Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection.
  • A. Hughes, M. Nei
  • Proceedings of the National Academy of Sciences…
  • 1989
    • Corpus ID: 25810130
To study the mechanism of maintenance of polymorphism at major histocompatibility complex (MHC) loci, synonymous and… Expand
Highly Cited
1988
Highly Cited
1988
Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
We detected large numbers of HLA-DR-positive reactive microglia (macrophages), along with Lewy bodies and free melanin, in the… Expand
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