Genes, MHC Class II

Known as: MHC Class II, Class II Genes, Class II Gene 
Genetic loci in the vertebrate major histocompatibility complex that encode polymorphic products which control the immune response to specific… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
The presence of post-translational regulation of MHC class II (MHC II) under physiological conditions has been demonstrated… (More)
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Highly Cited
2007
Highly Cited
2007
Mesenchymal stromal cells (MSC) possess immunosuppressive properties, yet when treated with IFN-gamma they acquire APC functions… (More)
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Highly Cited
2007
Highly Cited
2007
We have found that MHC class II (MHC II) molecules exhibit a distinctive organization on the dendritic cell (DC) plasma membrane… (More)
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Highly Cited
2006
Highly Cited
2006
We previously reported a novel E3 ubiquitin ligase (E3), designated as c-MIR, which targets B7-2 to lysosomal degradation and… (More)
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Highly Cited
2005
Highly Cited
2005
We found IL-6-STAT3 pathway suppresses MHC class II (MHCII) expression on dendritic cells (DCs) and attenuates T cell activation… (More)
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Highly Cited
2000
Highly Cited
2000
In B-cell lymphomas, loss of human leukocyte antigen (HLA) class I and II molecules might contribute to immune escape from CD8… (More)
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Highly Cited
1996
Highly Cited
1996
CIITA activates the expression of multiple genes involved in antigen presentation and it is believed to be required for both… (More)
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Highly Cited
1994
Highly Cited
1994
Targeting of MHC class II molecules to the endocytic compartment where they encounter processed antigen is determined by the… (More)
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Highly Cited
1987
Highly Cited
1987
Over half of the inherited predisposition to insulin-dependent diabetes mellitus maps to the region of chromosome 6 that contains… (More)
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1985
1985
Class II (or Ia) antigens are highly polymorphic surface molecules which are essential for the cellular interactions involved in… (More)
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