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HLA Class II Histocompatibility Antigen Gamma Chain, human

Known as: HLA-DR Antigens-Associated Invariant Chain, Ia Antigen-Associated Invariant Chain, HLA Class II Histocompatibility Antigen Gamma Chain 
HLA class II histocompatibility antigen gamma chain (296 aa, ~34 kDa) is encoded by the human CD74 gene. This protein plays a role in MHC class II… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Immune responses are initiated and primed by dendritic cells (DCs) that cross-present exogenous antigen. The chaperone CD74… Expand
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Highly Cited
2011
Highly Cited
2011
c-Jun N-terminal kinase (JNK) is a member of the mitogen-activated protein kinase (MAPK) family and controls essential processes… Expand
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Highly Cited
2009
Highly Cited
2009
MINT‐7234499: CXCR4 (uniprotkb:P61073) and CD74 (uniprotkb:P04233) colocalize (MI:0403) by fluorescence microscopy (MI:0416) 
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Highly Cited
2009
Highly Cited
2009
Macrophage migration inhibitory factor (MIF) is a pleiotropic proinflammatory cytokine involved in acute lung injury and other… Expand
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Highly Cited
2008
Highly Cited
2008
Macrophage migration inhibitory factor (MIF) is an upstream activator of innate immunity that regulates subsequent adaptive… Expand
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Highly Cited
2006
Highly Cited
2006
CD74 is an integral membrane protein that was thought to function mainly as an MHC class II chaperone. However, CD74 was recently… Expand
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Highly Cited
2005
Highly Cited
2005
Purpose: IMMU-110 is a drug immunoconjugate composed of doxorubicin conjugated to the humanized anti-CD74 monoclonal antibody… Expand
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Highly Cited
2004
Highly Cited
2004
Purpose: CD74 (HLA-DR-associated invariant chain) plays a role in antigen presentation. In addition to its expression on antigen… Expand
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Highly Cited
2003
Highly Cited
2003
Macrophage migration inhibitory factor (MIF) accounts for one of the first cytokine activities to have been described, and it has… Expand
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Highly Cited
1992
Highly Cited
1992
The MHC class II-associated invariant chain behaves as a resident endoplasmic reticulum protein in the absence of class II… Expand
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