HLA Class II Histocompatibility Antigen Gamma Chain, human

Known as: HLA-DR Antigens-Associated Invariant Chain, Ia Antigen-Associated Invariant Chain, HLA Class II Histocompatibility Antigen Gamma Chain 
HLA class II histocompatibility antigen gamma chain (296 aa, ~34 kDa) is encoded by the human CD74 gene. This protein plays a role in MHC class II… (More)
National Institutes of Health

Papers overview

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2012
2012
Immune responses are initiated and primed by dendritic cells (DCs) that cross-present exogenous antigen. The chaperone CD74… (More)
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2012
2012
Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that plays a role in innate and adaptive immunity… (More)
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2011
2011
c-Jun N-terminal kinase (JNK) is a member of the mitogen-activated protein kinase (MAPK) family and controls essential processes… (More)
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Highly Cited
2009
Highly Cited
2009
MIF is a chemokine-like inflammatory mediator that triggers leukocyte recruitment by binding to CXCR2 and CXCR4. MIF also… (More)
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Highly Cited
2009
Highly Cited
2009
Although metabolic derangement plays a central role in diabetic nephropathy, a better understanding of secondary mediators of… (More)
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Highly Cited
2008
Highly Cited
2008
Dendritic cells (DCs) sample peripheral tissues of the body in search of antigens to present to T cells. This requires two… (More)
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Highly Cited
2008
Highly Cited
2008
Macrophage migration inhibitory factor (MIF) is an upstream activator of innate immunity that regulates subsequent adaptive… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE CD74 (HLA-DR-associated invariant chain) plays a role in antigen presentation. In addition to its expression on antigen… (More)
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Highly Cited
2003
Highly Cited
2003
Macrophage migration inhibitory factor (MIF) accounts for one of the first cytokine activities to have been described, and it has… (More)
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Highly Cited
1992
Highly Cited
1992
The MHC class II-associated invariant chain behaves as a resident endoplasmic reticulum protein in the absence of class II… (More)
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