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Antigen-Presenting Cells

Known as: Dendritic cell, Antigen presenting cell, Antigen presenting cells 
A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells… 
National Institutes of Health

Related topics

Related topics

22 relations
Antigen PresentationAntigen ProcessingAntigen SensitizationBone Marrow Cells

Narrower (4)

Dendritic CellsHepatic macrophageLangerhans cellmacrophage

Broader (1)

Immune system

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Differential Lysosomal Proteolysis in Antigen-Presenting Cells Determines Antigen Fate
Antigen-presenting cells (APCs) internalize antigens and present antigen-derived peptides to T cells. Although APCs have been… 
Highly Cited
2005
Highly Cited
2005
Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model.
Review
1999
Review
1999
The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids.
Recent studies have identified the CD1 family of proteins as novel antigen-presenting molecules encoded by genes located outside… 
Highly Cited
1998
Highly Cited
1998
Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns.
Current thinking attributes the balance between T helper 1 (Th1) and Th2 cytokine response patterns in immune responses to the… 
Highly Cited
1997
Highly Cited
1997
Class I–restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8+ T Cells
In this report, we show that cross-presentation of self-antigens can lead to the peripheral deletion of autoreactive CD8+ T cells… 
Review
1994
Review
1994
Acquisition of lymphokine-producing phenotype by CD4+ T cells.
Naive CD4+ T cells when stimulated produce IL-2 as their major lymphokine. Upon priming, these cells develop into cells that… 
Highly Cited
1993
Highly Cited
1993
Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages
Class II major histocompatibility complex (Ia)-bearing dendritic cells (DC) from airway epithelium and lung parenchyma express… 
Review
1987
Review
1987
The lymphocyte function-associated LFA-1, CD2, and LFA-3 molecules: cell adhesion receptors of the immune system.
Cell adhesion molecules are thought to play an important role in guiding cell migration and localization in the development of… 
Review
1987
Review
1987
The basis for the immunoregulatory role of macrophages and other accessory cells.
Macrophages handle extracellular proteins and secrete diverse bioactive molecules and, therefore, influence the physiology of… 
Highly Cited
1983
Highly Cited
1983
Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing
We examined the ability of a set of cloned chicken ovalbumin (cOVA)- specific, Id-restricted, T cell hybridomas to produce… 
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