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Antigen-Presenting Cells

Known as: Dendritic cell, Antigen presenting cell, Antigen presenting cells 
A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells… 
National Institutes of Health

Related topics

Related topics

22 relations
Antigen PresentationAntigen ProcessingAntigen SensitizationBone Marrow Cells

Narrower (4)

Dendritic CellsHepatic macrophageLangerhans cellmacrophage

Broader (1)

Immune system

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Natural Alpha Interferon-Producing Cells Respond to Human Immunodeficiency Virus Type 1 with Alpha Interferon Production and Maturation into Dendritic Cells
ABSTRACT Natural alpha interferon (IFN-α)-producing cells (IPCs) are now recognized as identical to plasmacytoid dendritic cell… 
Highly Cited
2001
Highly Cited
2001
Comparative analysis of necrotic and apoptotic tumor cells as a source of antigen(s) in dendritic cell-based immunization.
There is considerable controversy as to whether necrotic (lysate) or apoptotic tumor cells serve as the superior source of… 
Review
2000
Review
2000
T cell activation and the cytoskeleton.
Ligation of the T cell antigen receptor (TCR) stimulates protein tyrosine kinases (PTKs), which regulate intracellular calcium… 
Highly Cited
1998
Highly Cited
1998
TGF-beta promotes immune deviation by altering accessory signals of antigen-presenting cells.
Macrophages incubated with OVA in the presence of TGF-beta2 induce immune deviation in vivo (impaired delayed hypersensitivity… 
Highly Cited
1997
Highly Cited
1997
Monocytes express Fas ligand upon CD4 cross-linking and induce CD4+ T cells apoptosis: a possible mechanism of bystander cell death in HIV infection.
Recent evidence indicates that death of uninfected lymphocytes by apoptosis plays an important role in the immunopathogenesis of… 
Highly Cited
1995
Highly Cited
1995
Costimulation with B7-1, IL-6, and IL-12 is sufficient for primary generation of murine antitumor cytolytic T lymphocytes in vitro.
The requirements for generating CD8+ CTLs against the mastocytoma P815 were first defined by using an allogeneic mixed lymphocyte… 
Highly Cited
1993
Highly Cited
1993
Specific interaction of lymphocyte function-associated antigen 3 with CD2 can inhibit T cell responses
Accessory cell surface molecules, such as T cell antigen CD2 and its ligand lymphocyte function-associated antigen 3 (LFA-3; CD58… 
Highly Cited
1990
Highly Cited
1990
IL-4 production by T cells from naive donors. IL-2 is required for IL-4 production.
Utilizing a sensitive and selective assay for IL-4, it was shown that lymph node T cells from naive mice could produce small… 
Highly Cited
1984
Highly Cited
1984
Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen.
A 17-amino acid tryptic peptide of chicken ovalbumin, designated P323-339, that substituted for processed antigen when presented… 
Highly Cited
1980
Highly Cited
1980
Antigen-reactive T cell clones. I. Transcomplementing hybrid I-A-region gene products function effectively in antigen presentation
Studies in our laboratory and elsewhere have shown that it is possible to propagate antigen-specific murine T cells in vitro with… 
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