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Antigen Processing

Known as: Antigen Processings 
The process by which foreign molecules are taken up by antigen presenting cells, proteolytically cleaved, and displayed on the cell surface in… 
National Institutes of Health

Related topics

Related topics

39 relations
Antigen PresentationAntigen-Presenting CellsAntigensB-Cell Receptor Complex

Papers overview

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Review
2005
Review
2005
The seven dirty little secrets of major histocompatibility complex class I antigen processing.
Every field has its dirty little secrets (DLSs): assumptions based on flimsy evidence, findings that directly contradict… 
Review
2003
Review
2003
The components of the proteasome system and their role in MHC class I antigen processing.
By generating peptides from intracellular antigens which are then presented to T cells, the ubiquitin/26S proteasome system plays… 
Highly Cited
2002
Highly Cited
2002
Proteasome, Transporter Associated with Antigen Processing, and Class I Genes in the Nurse Shark Ginglymostoma cirratum: Evidence for a Stable Class I Region and MHC Haplotype Lineages1
Cartilaginous fish (e.g., sharks) are derived from the oldest vertebrate ancestor having an adaptive immune system, and thus are… 
Highly Cited
2001
Highly Cited
2001
Lack of tumor recognition by hTERT peptide 540–548‐specific CD8+ T cells from melanoma patients reveals inefficient antigen processing
Telomerase is a ribonucleoprotein complex responsible for the maintenance of the length of the telomeres during cell division… 
Highly Cited
1997
Highly Cited
1997
The generation of MHC class I-associated peptides is only partially inhibited by proteasome inhibitors: involvement of nonproteasomal cytosolic proteases in antigen processing?
The proteasome is believed to participate in the generation of a large percentage of peptide ligands for MHC class I molecules… 
Highly Cited
1997
Highly Cited
1997
The effect of the proteasome inhibitor lactacystin on the presentation of transporter associated with antigen processing (TAP)-dependent and TAP-independent peptide epitopes by class I molecules.
Cells were treated with two proteolytic inhibitors, N-acetyl-leucyl-leucyl-norleucinal and lactacystin, the latter reported to be… 
Highly Cited
1994
Highly Cited
1994
Major Histocompatibility Complex–Encoded Antigen Processing Gene Polymorphism in IDDM
Susceptibility to insulin-dependent diabetes mellitus (IDDM) is greatly influenced by polymorphisms in the genes of the class II… 
Highly Cited
1991
Highly Cited
1991
Reduction of disulfide bonds during antigen processing: evidence from a thiol-dependent insulin determinant
Previous studies have demonstrated that insulin, like other protein antigens, requires processing in metabolically active antigen… 
Highly Cited
1988
Highly Cited
1988
Antigen presentation to HLA class II-restricted measles virus-specific T-cell clones can occur in the absence of the invariant chain.
A human fibroblast line expressing HLA-DR1 antigen on its surface was generated by transfection with DR alpha and DR beta cDNAs… 
Highly Cited
1985
Highly Cited
1985
The molecular basis of the requirement for antigen processing of pigeon cytochrome c prior to T cell activation.
Antigen-induced activation of T lymphocytes that co-recognize Ia molecules has been shown to require an antigen-processing step… 
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