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Antigen Processing
Known as:
Antigen Processings
The process by which foreign molecules are taken up by antigen presenting cells, proteolytically cleaved, and displayed on the cell surface in…
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National Institutes of Health
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Related topics
Related topics
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Antigen Presentation
Antigen-Presenting Cells
Antigens
B-Cell Receptor Complex
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
The seven dirty little secrets of major histocompatibility complex class I antigen processing.
J. Yewdell
Immunological Reviews
2005
Corpus ID: 35292016
Every field has its dirty little secrets (DLSs): assumptions based on flimsy evidence, findings that directly contradict…
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Review
2003
Review
2003
The components of the proteasome system and their role in MHC class I antigen processing.
Elke Krüger
,
Ulrike Kuckelkorn
,
A. Sijts
,
P. Kloetzel
Reviews of Physiology, Biochemistry and…
2003
Corpus ID: 44633538
By generating peptides from intracellular antigens which are then presented to T cells, the ubiquitin/26S proteasome system plays…
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Highly Cited
2002
Highly Cited
2002
Proteasome, Transporter Associated with Antigen Processing, and Class I Genes in the Nurse Shark Ginglymostoma cirratum: Evidence for a Stable Class I Region and MHC Haplotype Lineages1
Y. Ohta
,
E. McKinney
,
M. Criscitiello
,
M. Flajnik
Journal of Immunology
2002
Corpus ID: 25295298
Cartilaginous fish (e.g., sharks) are derived from the oldest vertebrate ancestor having an adaptive immune system, and thus are…
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Highly Cited
2001
Highly Cited
2001
Lack of tumor recognition by hTERT peptide 540–548‐specific CD8+ T cells from melanoma patients reveals inefficient antigen processing
M. Ayyoub
,
M. Migliaccio
,
+6 authors
D. Valmori
European Journal of Immunology
2001
Corpus ID: 36872671
Telomerase is a ribonucleoprotein complex responsible for the maintenance of the length of the telomeres during cell division…
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Highly Cited
1997
Highly Cited
1997
The generation of MHC class I-associated peptides is only partially inhibited by proteasome inhibitors: involvement of nonproteasomal cytosolic proteases in antigen processing?
A. Vinitsky
,
L. C. Antón
,
H. L. Snyder
,
M. Orłowski
,
J. Bennink
,
J. Yewdell
Journal of Immunology
1997
Corpus ID: 25556634
The proteasome is believed to participate in the generation of a large percentage of peptide ligands for MHC class I molecules…
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Highly Cited
1997
Highly Cited
1997
The effect of the proteasome inhibitor lactacystin on the presentation of transporter associated with antigen processing (TAP)-dependent and TAP-independent peptide epitopes by class I molecules.
Ailin Bai
,
James Forman
Journal of Immunology
1997
Corpus ID: 44400350
Cells were treated with two proteolytic inhibitors, N-acetyl-leucyl-leucyl-norleucinal and lactacystin, the latter reported to be…
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Highly Cited
1994
Highly Cited
1994
Major Histocompatibility Complex–Encoded Antigen Processing Gene Polymorphism in IDDM
P. van Endert
,
R. Liblau
,
+5 authors
H. Mcdevitt
Diabetes
1994
Corpus ID: 29302609
Susceptibility to insulin-dependent diabetes mellitus (IDDM) is greatly influenced by polymorphisms in the genes of the class II…
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Highly Cited
1991
Highly Cited
1991
Reduction of disulfide bonds during antigen processing: evidence from a thiol-dependent insulin determinant
P. Jensen
Journal of Experimental Medicine
1991
Corpus ID: 15905474
Previous studies have demonstrated that insulin, like other protein antigens, requires processing in metabolically active antigen…
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Highly Cited
1988
Highly Cited
1988
Antigen presentation to HLA class II-restricted measles virus-specific T-cell clones can occur in the absence of the invariant chain.
R. Sékaly
,
S. Jacobson
,
J. Richert
,
C. Tonnelle
,
H. McFarland
,
Eric O Long
Proceedings of the National Academy of Sciences…
1988
Corpus ID: 19934776
A human fibroblast line expressing HLA-DR1 antigen on its surface was generated by transfection with DR alpha and DR beta cDNAs…
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Highly Cited
1985
Highly Cited
1985
The molecular basis of the requirement for antigen processing of pigeon cytochrome c prior to T cell activation.
Z. Kovač
,
R. Schwartz
Journal of Immunology
1985
Corpus ID: 22167356
Antigen-induced activation of T lymphocytes that co-recognize Ia molecules has been shown to require an antigen-processing step…
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