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B-Cell Receptor Complex

Known as: B Cell Receptor Complex, BCR, B-Cell Receptor 
A membrane bound protein complex comprised of an immunoglobulin molecule associated with a heterodimer, called CD79, containing one CD79A protein and… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
B cells and the antibodies they produce have a deeply penetrating influence on human physiology. Here, we review current… Expand
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Highly Cited
2005
Highly Cited
2005
The Bcr-Abl tyrosine kinase oncogene causes chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive (Ph+) acute… Expand
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Highly Cited
2003
Highly Cited
2003
Heat shock protein 90 (Hsp90) is a molecular chaperone that plays a key role in the conformational maturation of oncogenic… Expand
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Review
2000
Review
2000
Chronic myeloid leukemia (CML) is probably the most extensively studied human malignancy. The discovery of the Philadelphia (Ph… Expand
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Highly Cited
2000
Highly Cited
2000
STI571 (formerly known as CGP 57148B) is a protein-tyrosine kinase inhibitor that is currently in clinical trials for the… Expand
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Review
1999
Review
1999
  • C. Sawyers
  • The New England journal of medicine
  • 1999
  • Corpus ID: 22146304
Over the past twenty years, clinical and laboratory studies have led to important new insights into the biology of chronic… Expand
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Highly Cited
1996
Highly Cited
1996
The bcr–abl oncogene, present in 95% of patients with chronic myelogenous leukemia (CML), has been implicated as the cause of… Expand
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Highly Cited
1990
Highly Cited
1990
Oncogenic activation of the proto-oncogene c-abl in human leukemias occurs as a result of the addition of exons from the gene bcr… Expand
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Highly Cited
1985
Highly Cited
1985
Human chronic myelogenous leukaemia is characterized by a reciprocal translocation between chromosomes 9 and 22 resulting in an… Expand
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Highly Cited
1984
Highly Cited
1984
We have identified and molecularly cloned 46 kb of human DNA from chromosome 22 using a probe specific for the Philadelphia (Ph… Expand
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