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Hepatic macrophage

Known as: Kupffer's cell, Kupffer Cells, Stellate Sinusoidal Macrophage 
Specialized phagocytic cells of the MONONUCLEAR PHAGOCYTE SYSTEM found on the luminal surface of the hepatic sinusoids. They filter bacteria and… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (4)

Antigen-Presenting CellsLiver parenchymaReticuloendothelial Systemcell type
Hepatic Stellate CellsHepatocyteImmune systemIto Cells

Narrower (1)

Kupffer cell sarcoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Hepatic fibrosis: It is time to go with hepatic stellate cell-specific therapeutic targets.
Review
2013
Review
2013
Nucleation of platelets with bloodborne pathogens on Kupffer cell precedes other innate immunity and contributes to bacterial clearance
Through the use of intravital imaging of the liver, we demonstrate a collaborative role for platelets with Kupffer cells (KCs) in… 
Highly Cited
2012
Highly Cited
2012
Increased Macrophage Migration Into Adipose Tissue in Obese Mice
Macrophage-mediated inflammation is a key component of insulin resistance; however, the initial events of monocyte migration to… 
Highly Cited
2012
Highly Cited
2012
Tim‐3/galectin‐9 signaling pathway mediates T‐cell dysfunction and predicts poor prognosis in patients with hepatitis B virus‐associated hepatocellular carcinoma
The interaction between T cell immunoglobulin‐ and mucin‐domain‐containing molecule (Tim‐3) expressed on T helper 1 (Th1) cells… 
Review
2006
Review
2006
Role of Kupffer cells in host defense and liver disease
Abstract: Kupffer cells (KC) constitute 80–90% of the tissue macrophages present in the body. They reside within the lumen of the… 
Review
2002
Review
2002
Activation of hepatic stellate cells--a key issue in liver fibrosis.
Hepatic fibrosis describes the presence of excess collagen due to new fiber formation, laid down as part of the tissue repair… 
Highly Cited
2000
Highly Cited
2000
Blood clearance rates of adenovirus type 5 in mice.
Persistence of adenovirus type 5 in blood has implications for the pathogenicity of the virus infection and for the use of this… 
Highly Cited
2000
Highly Cited
2000
Importance of Kupffer cells for T-cell-dependent liver injury in mice.
Highly Cited
1996
Highly Cited
1996
Tissue inhibitor of metalloproteinase‐1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis
Liver fibrosis results from a relative imbalance between synthesis and degradation of matrix proteins. We have previously… 
Highly Cited
1989
Highly Cited
1989
Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells
A metabolic pathway by which L-arginine (L-arg) is converted to the biologically active compound NO. has recently been described… 
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