Hepatic macrophage

Known as: Kupffer's Cell, Kupffer Cells, Stellate Sinusoidal Macrophage 
Specialized phagocytic cells of the MONONUCLEAR PHAGOCYTE SYSTEM found on the luminal surface of the hepatic sinusoids. They filter bacteria and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1961-2017
05010019612017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Inflammatory cell infiltration in the liver is a hallmark of nonalcoholic steatohepatitis (NASH). The chemokine-chemokine… (More)
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Highly Cited
2012
Highly Cited
2012
Macrophage-mediated inflammation is a key component of insulin resistance; however, the initial events of monocyte migration to… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Interleukin-8 (IL-8, CXCL8) is a potent chemoattractant for neutrophils and contributes to acute liver inflammation… (More)
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Highly Cited
2010
Highly Cited
2010
Recruited adipose tissue macrophages contribute to chronic and low-grade inflammation causing insulin resistance in obesity… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE Increased activity of the innate immune system has been implicated in the pathogenesis of the dyslipidemia and insulin… (More)
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Highly Cited
2008
Highly Cited
2008
Macrophage infiltration and activation in metabolic tissues underlie obesity-induced insulin resistance and type 2 diabetes… (More)
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Highly Cited
2003
Highly Cited
2003
Hepatocyte apoptosis by death receptors, hepatic inflammation, and fibrosis are prominent features of liver diseases. However… (More)
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Highly Cited
2000
Highly Cited
2000
Persistence of adenovirus type 5 in blood has implications for the pathogenicity of the virus infection and for the use of this… (More)
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Highly Cited
1998
Highly Cited
1998
Liver fibrosis results from the excessive secretion of matrix proteins by hepatic stellate cells (HSC), which proliferate during… (More)
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Highly Cited
1995
Highly Cited
1995
Acetaminophen is a mild analgesic and antipyretic agent that is safe and effective when taken in therapeutic doses. Ingestion of… (More)
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