Skip to search formSkip to main contentSkip to account menu

Hepatic macrophage

Known as: Kupffer's cell, Kupffer Cells, Stellate Sinusoidal Macrophage 
Specialized phagocytic cells of the MONONUCLEAR PHAGOCYTE SYSTEM found on the luminal surface of the hepatic sinusoids. They filter bacteria and… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (4)

Antigen-Presenting CellsLiver parenchymaReticuloendothelial Systemcell type
Hepatic Stellate CellsHepatocyteImmune systemIto Cells

Narrower (1)

Kupffer cell sarcoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
GASTROINTESTINAL , HEPATOBILIARY , AND PANCREATIC PATHOLOGY Gut Bacteria Drive Kupffer Cell Expansion via MAMP-Mediated ICAM-1 Induction on Sinusoidal Endothelium and In fl uence Preservation…
opyright a 2013 American Society for Inve ublished by Elsevier Inc. All rights reserved ttp://dx.doi.org/10.1016/j.ajpath.2012.09… 
Highly Cited
2004
Highly Cited
2004
NK Cells, but Not NKT Cells, Are Involved in Pseudomonas aeruginosa Exotoxin A-Induced Hepatotoxicity in Mice1
Pseudomonas aeruginosa exotoxin A (PEA) causes T cell- and Kupffer cell (KC)-dependent liver injury in mice. TNF-α as well as IL… 
Highly Cited
2002
Highly Cited
2002
Functional heterogeneity of the kupffer cell population is involved in the mechanism of gadolinium chloride in rats administered endotoxin.
BACKGROUND The purpose of this study was to determine if evidence of functional heterogeneity between subtypes of the Kupffer… 
2002
2002
Intestinal damage mediated by Kupffer cells in rats with endotoxemia.
AIM To determine the in vivo effects of phagocytic blockade of Kupffer cell (KC) on the release of proinflammatory cytokines in… 
Highly Cited
2001
Highly Cited
2001
MICROCIRCULATORY FAILURE AFTER RAT LIVER TRANSPLANTATION IS RELATED TO KUPFFER CELL-DERIVED OXIDANT STRESS BUT NOT INVOLVED IN EARLY GRAFT DYSFUNCTION1
Background. Microcirculatory failure, activation of Kupffer cells (KC), and the formation of reactive oxygen species (ROS) are… 
Highly Cited
1999
Highly Cited
1999
Inhibition of caspase activity prevents CD95‐mediated hepatic microvascular perfusion failure and restores Kupffer cell clearance capacity
Using a murine model, we studied the effect of agonistic anti‐CD95 antibodies (aCD95) on sinusoidal lining cells and a potential… 
Highly Cited
1998
Highly Cited
1998
Regulation of CD95 (APO‐1/Fas) receptor and ligand expression by lipopolysaccharide and dexamethasone in parenchymal and nonparenchymal rat liver cells
The effect of lipopolysaccharide (LPS) on the expression of CD95 (APO‐1/Fas) receptor and ligand (CD95L) was studied in primary… 
Highly Cited
1994
Highly Cited
1994
ROLE OF KUPFFER CELLS IN INTERLEUKIN‐6 RELEASE FOLLOWING TRAUMA‐HEMORRHAGE AND RESUSCITATION
Although Interleukin-6 (IL-6) plays an important role in the pathophysiology of traumahemorrhage and resuscitation, the cellular… 
1991
1991
Structure of the gene for a carbohydrate-binding receptor unique to rat kupffer cells.
Highly Cited
1985
Highly Cited
1985
Impaired Kupffer cell function precedes development of secondary amyloidosis
It has been demonstrated previously that the acute phase reactant, serum amyloid A (SAA), is subject to degradation by surface… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)