Hepatocyte

Known as: Hepatic Cell, Hepatocytes, Cell, Hepatic 
The main structural component of the LIVER. They are specialized EPITHELIAL CELLS that are organized into interconnected plates called lobules.
National Institutes of Health

Related topics

Related topics

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BCLC Stage A Hepatocellular CarcinomaBCLC Stage B Adult Hepatocellular CarcinomaBCLC Stage B Hepatocellular CarcinomaBCLC Stage C Hepatocellular Carcinoma
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Hepatic Stellate CellsHepatic macrophageProtoplasm

Papers overview

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Review
2017
Review
2017
Liver inflammation and fibrosis.
Chronic liver inflammation leads to fibrosis and cirrhosis, which is the 12th leading cause of death in the United States… (More)
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Review
2017
Review
2017
Concise Review: Liver Regenerative Medicine: From Hepatocyte Transplantation to Bioartificial Livers and Bioengineered Grafts.
Donor organ shortage is the main limitation to liver transplantation as a treatment for end-stage liver disease and acute liver… (More)
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Review
2016
Review
2016
Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease.
The exposure of hepatocytes to high concentrations of lipids and carbohydrates and the ensuing hepatocellular injury are termed… (More)
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Highly Cited
2011
Highly Cited
2011
Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors
The generation of functional hepatocytes independent of donor liver organs is of great therapeutic interest with regard to… (More)
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Highly Cited
2010
Highly Cited
2010
Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells.
UNLABELLED There exists a worldwide shortage of donor livers available for orthotropic liver transplantation and hepatocyte… (More)
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Highly Cited
2009
Highly Cited
2009
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene.
Hippo-Lats-Yorkie signaling regulates tissue overgrowth and tumorigenesis in Drosophila. We show that the Mst1 and Mst2 protein… (More)
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Highly Cited
2005
Highly Cited
2005
IKKβ Couples Hepatocyte Death to Cytokine-Driven Compensatory Proliferation that Promotes Chemical Hepatocarcinogenesis
IkappaB kinase beta (IKKbeta), required for NF-kappaB activation, links chronic inflammation with carcinogenesis. We investigated… (More)
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Highly Cited
2003
Highly Cited
2003
Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes
Recent studies have suggested that bone marrow cells possess a broad differentiation potential, being able to form new liver… (More)
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Highly Cited
1996
Highly Cited
1996
Mutations in the hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young (MODY1)
THE disease maturity-onset diabetes of the young (MODY) is a genetically heterogeneous monogenic form of non-insulin-dependent… (More)
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Highly Cited
1989
Highly Cited
1989
Molecular cloning and expression of human hepatocyte growth factor
HEPATOCYTE growth factor (HGF) is the most potent mitogen for mature parenchyma! hepatocytes in primary culture, and seems to be… (More)
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