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Antibodies, Monoclonal, Humanized

Known as: Humanized Monoclonal Antibody, Antibodies, Monoclonal, Humanized [Chemical/Ingredient], Antibodies, Humanized 
Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Tumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules… Expand
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Highly Cited
2010
Highly Cited
2010
Monoclonal antibodies represent an attractive therapeutic tool as they are highly specific for their targets, convey effector… Expand
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Highly Cited
2009
Highly Cited
2009
Targeted gene disruption in rats paves the way for new human disease models. The toolbox of rat genetics currently lacks the… Expand
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Highly Cited
2009
Highly Cited
2009
Purpose: A significant fraction of HER2-overexpressing breast cancers exhibit resistance to the HER2 antibody trastuzumab… Expand
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Highly Cited
2008
Highly Cited
2008
The glycated form of a basic recombinant humanized monoclonal antibody (rhuMAb) was separated and quantitated by boronate… Expand
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Highly Cited
2007
Highly Cited
2007
We have identified a single tryptophan (Trp) residue responsible for loss of binding and biological activity upon ultraviolet (UV… Expand
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Highly Cited
2006
Highly Cited
2006
Conjugates of the anti-CanAg humanized monoclonal antibody huC242 with the microtubule-formation inhibitor DM1 (a maytansinoid… Expand
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Highly Cited
2006
Highly Cited
2006
AbegrinTM (MEDI-522 or VitaxinTM), a humanized monoclonal antibody against human integrin αvβ3, is in clinical trials for cancer… Expand
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Highly Cited
2004
Highly Cited
2004
Integrins of the αv family, such as αvβ3 and αvβ5, are implicated in tumor‐induced angiogenesis; but their role in tumor growth… Expand
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Review
2003
Review
2003
The HER family of transmembrane tyrosine kinase receptors is composed of four members, BER1 to HER4. HER2 is a ligand-orphan… Expand
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