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Antibodies, Monoclonal, Humanized

Known as: Humanized Monoclonal Antibody, Antibodies, Monoclonal, Humanized [Chemical/Ingredient], Antibodies, Humanized 
Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Monoclonal antibodies represent an attractive therapeutic tool as they are highly specific for their targets, convey effector… Expand
Highly Cited
2009
Highly Cited
2009
Targeted gene disruption in rats paves the way for new human disease models. The toolbox of rat genetics currently lacks the… Expand
Review
2009
Review
2009
Nanoscience and Nanotechnology have found their way into the fields of Biotechnology and Medicine. Nanoparticles by themselves… Expand
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Highly Cited
2009
Highly Cited
2009
Purpose: A significant fraction of HER2-overexpressing breast cancers exhibit resistance to the HER2 antibody trastuzumab… Expand
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Highly Cited
2008
Highly Cited
2008
The glycated form of a basic recombinant humanized monoclonal antibody (rhuMAb) was separated and quantitated by boronate… Expand
Highly Cited
2007
Highly Cited
2007
We have identified a single tryptophan (Trp) residue responsible for loss of binding and biological activity upon ultraviolet (UV… Expand
Highly Cited
2006
Highly Cited
2006
Conjugates of the anti-CanAg humanized monoclonal antibody huC242 with the microtubule-formation inhibitor DM1 (a maytansinoid… Expand
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Highly Cited
2005
Highly Cited
2005
Antibodies and small molecule tyrosine kinase inhibitors targeting ErbB2 exhibit distinct, noncross resistant mechanisms of… Expand
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Review
2003
Review
2003
The HER family of transmembrane tyrosine kinase receptors is composed of four members, BER1 to HER4. HER2 is a ligand-orphan… Expand
Highly Cited
1991
Highly Cited
1991
Antibody therapy holds great promise for the treatment of cancer, autoimmune disorders, and viral infections. Murine monoclonal… Expand
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