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Antibodies, Monoclonal, Humanized

Known as: Humanized Monoclonal Antibody, Antibodies, Monoclonal, Humanized [Chemical/Ingredient], Antibodies, Humanized 
Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant… 
National Institutes of Health

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89Zr-bevacizumabAVE1642BIIB036BIW-8962
In Bloodantigen binding

Papers overview

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Highly Cited
2014
Highly Cited
2014
Safety and tolerability of LBR-101, a humanized monoclonal antibody that blocks the binding of CGRP to its receptor: Results of the Phase 1 program
Background LBR-101 is a fully humanized monoclonal antibody that binds to calcitonin gene-related peptide. Objective The… 
Highly Cited
2013
Highly Cited
2013
Monoclonal antibody humanness score and its applications
BackgroundMonoclonal antibody therapeutics are rapidly gaining in popularity for the treatment of a myriad of diseases, ranging… 
Review
2011
Review
2011
Pharmacokinetics and Pharmacodynamics of Mepolizumab, an Anti-Interleukin-5 Monoclonal Antibody
Mepolizumab is a fully humanized monoclonal antibody (IgG1/κ) targeting human interleukin-5 (IL-5), a key haematopoietin needed… 
Review
2009
Review
2009
Antibody-conjugated nanoparticles for biomedical applications
Nanoscience and Nanotechnology have found their way into the fields of Biotechnology and Medicine. Nanoparticles by themselves… 
Highly Cited
2009
Highly Cited
2009
Inhibition of Mammalian Target of Rapamycin Is Required for Optimal Antitumor Effect of HER2 Inhibitors against HER2-Overexpressing Cancer Cells
Purpose: A significant fraction of HER2-overexpressing breast cancers exhibit resistance to the HER2 antibody trastuzumab… 
Highly Cited
2007
Highly Cited
2007
Identification of a single tryptophan residue as critical for binding activity in a humanized monoclonal antibody against respiratory syncytial virus.
We have identified a single tryptophan (Trp) residue responsible for loss of binding and biological activity upon ultraviolet (UV… 
Highly Cited
2005
Highly Cited
2005
Development of humanized antibodies as cancer therapeutics.
Highly Cited
2002
Highly Cited
2002
Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis.
Review
2002
Review
2002
Myeloma expression systems.
1995
1995
Mass spectrometry of the humanized monoclonal antibody CAMPATH 1H.
Two mass spectrometric techniques, electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI) have… 
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