FAQ

complement pathway

Known as: complement pathways 
The complement pathway consists of a series of over thirty proteins in plasma that are part of the immune response. Activation of the complement… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2017
05010019712017

Related topics

Related topics

10 relations

Broader (1)

Antigen-Antibody Reactions
C2 wt AlleleC4A wt AlleleC4B wt AlleleComplement C2, human
(More)

Narrower (3)

Complement ActivationComplement Pathway, AlternativeComplement Pathway, Classical

Related mentions per year

Related mentions per year

1945-2018
19401960198020002020
complement pathway
Complement Activation
Antigen-Antibody Reactions
C2 wt Allele
Complement Pathway, Alternative
Complement Pathway, Classical

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Variation in complement factor 3 is associated with risk of age-related macular degeneration
The association of variants in complement factors H and B with age-related macular degeneration has led to more intense genetic… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
The intricate system of serum complement proteins provides resistance to infection. A pivotal step in the complement pathway is… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Gastrointestinal ischemia-reperfusion injury is lectin complement pathway dependent without involving C1q.
Complement activation plays an important role in local and remote tissue injury associated with gastrointestinal ischemia… (More)
  • figure 1
  • table I
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Human M-ficolin is a secretory protein that activates the lectin complement pathway.
Three types of ficolins have been identified in humans: L-ficolin, M-ficolin, and H-ficolin. Similar to mannose-binding lectin, L… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice.
The complement system is an important component of the innate immune response to bacterial pathogens, including Streptococcus… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Complement activation after oxidative stress: role of the lectin complement pathway.
The complement system plays an important role in mediating tissue injury after oxidative stress. The role of mannose-binding… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Abrogation of the alternative complement pathway by targeted deletion of murine factor B.
To investigate the role of complement protein factor B (Bf) and alternative pathway activity in vivo, and to test the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease
Serum mannose-binding protein (MBP) is a C-type lectin that binds to terminal mannose and N-acetylglucosamine moieties present on… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Adipsin and an endogenous pathway of complement from adipose cells.
The alternative complement pathway is best known for its role in humoral suppression of infectious agents. We have previously… (More)
Is this relevant?
Highly Cited
1989
Highly Cited
1989
Activation of the classical complement pathway in brain tissue of Alzheimer patients.
Positive immunohistochemical staining of Alzheimer brain tissue was obtained with antibodies to proteins associated with… (More)
Is this relevant?