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Complement Pathway, Alternative

Known as: complement cascade, alternative pathway, Alternative Complement Pathway, complement activation, alternative pathway 
Complement activation initiated by the interaction of microbial ANTIGENS with COMPLEMENT C3B. When COMPLEMENT FACTOR B binds to the membrane-bound… 
National Institutes of Health

Related topics

Related topics

13 relations
CFD wt AlleleCFH wt AlleleCFP wt AlleleComplement Factor B

Broader (1)

complement pathway

Papers overview

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Highly Cited
2001
Highly Cited
2001
The gene for alternative oxidase-2 (AOX2) from Arabidopsis thaliana consists of five exons unlike other AOX genes and is transcribed at an early stage during germination.
We investigated the expressions of genes for alternative oxidase (AOX1a, AOX1b, AOX1c and AOX2) and genes for cytochrome c… 
Highly Cited
1995
Highly Cited
1995
Diversity of Sites for Measles Virus Binding and for Inactivation of Complement C3b and C4b on Membrane Cofactor Protein CD46 (*)
The complement system membrane cofactor protein (MCP) CD46 serves as a C3b/C4b inactivating factor for the protection of host… 
Highly Cited
1994
Highly Cited
1994
The interaction of glycoprotein C of herpes simplex virus types 1 and 2 with the alternative complement pathway.
Glycoprotein C (gC) of herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2) binds the human complement fragment C3b, but the two… 
Highly Cited
1989
Highly Cited
1989
Activation and binding of opsonic fragments of C3 on encapsulated Cryptococcus neoformans by using an alternative complement pathway reconstituted from six isolated proteins
Encapsulated Cryptococcus neoformans yeast cells are potent activators of the complement system. We examined the interaction of… 
Highly Cited
1981
Highly Cited
1981
Host modification of Sindbis virus sialic acid content influences alternative complement pathway activation and virus clearance.
Previous studies have shown that Sindbis virus, an enveloped alphavirus of the togavirus group, activates the alternative… 
Highly Cited
1980
Highly Cited
1980
Antibody-independent activation of the alternative complement pathway by measles virus-infected cells.
When HeLa cells acutely infected with measles virus were incubated in a mixture containing only the six proteins of the… 
Highly Cited
1979
Highly Cited
1979
Inhibition of alternative complement pathway opsonization by group A streptococcal M protein.
Group A streptococcal M protein is known to be antiphagocytic; however, the exact basis for this property has not been… 
Highly Cited
1976
Highly Cited
1976
A simple method for the determination of complement receptor-bearing mononuclear cells.
A simple method is described for the identification of mononuclear cells bearing the complement receptor. Gram-negative bacteria… 
Highly Cited
1975
Highly Cited
1975
Initiation of C3 cleavage in the alternative complement pathway.
The capacity of C3 and 125I-C3 to interact with B and D to generate a C3 convertase was recognized by identification of C3b and… 
Highly Cited
1972
Highly Cited
1972
Inactivator of the third component of complement as an inhibitor in the properdin pathway.
Evidence has been obtained that a single protein, known to modulate classical complement activation, also acts as an inhibitor in… 
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