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Complement Pathway, Alternative

Known as: complement cascade, alternative pathway, Alternative Complement Pathway, complement activation, alternative pathway 
Complement activation initiated by the interaction of microbial ANTIGENS with COMPLEMENT C3B. When COMPLEMENT FACTOR B binds to the membrane-bound… 
National Institutes of Health

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13 relations
CFD wt AlleleCFH wt AlleleCFP wt AlleleComplement Factor B

Broader (1)

complement pathway

Papers overview

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1986
1986
Evasion of the alternative complement pathway by metacyclic trypomastigotes of Trypanosoma cruzi: dependence on the developmentally regulated synthesis of surface protein and N-linked carbohydrate.
Epimastigotes (EPI) of Trypanosoma cruzi are highly sensitive to lysis in fresh normal human serum by the alternative complement… 
Review
1984
Review
1984
Interactions between the alternative complement pathway and proteases of the coagulation system.
The Complement system consists of more than twenty components and regulatory plasma proteins involved in both specific (immune… 
1983
1983
Opsonization of various capsular (K) E. coli by the alternative complement pathway.
A virulence factor of E. coli K-1 is its capacity to avoid opsonization via the alternative complement pathway (ACP). Since it is… 
1983
1983
Surface-dependent modulation by H of C5 cleavage by the cell-bound alternative pathway C5 convertase of human complement.
Regulation by H of formation of the C3 and C5 alternative pathway convertases of complement on cells is dependent on such… 
1981
1981
Enhanced alternative complement pathway-dependent degradation of soluble immunoglobulin aggregates by macrophages.
The role of complement in the processing of soluble immune aggregates by guinea-pig peritoneal macrophages was studied in a… 
1979
1979
The role of antibody and complement in phagocytosis by rabbit alveolar macrophages.
The relative importance of antibody and complement in the phagocytosis of Staphylococcus aureus and Pseudomonas aeruginosa, two… 
1978
1978
Homozygous C2 deficiency with fulminant lupus erythematosus: severe nephritis via the alternative complement pathway.
Absence of C2 was identified in an 18-year-old white male with progressive and rapidly fatal lupus nephritis. Genetic studies of… 
1977
1977
Human factor D of the alternative complement pathway: purification and characterization.
D was purified to homogeneity from outdated human plasma by successive chromatography on Bio Rex 70, Sephadex G-200, Bio Rex 70… 
1976
1976
Serum factors activating the alternative complement pathway in autoimmune disease: description of two different factors from patients with systemic lupus erythematosus.
Serum factors which activated the alternative pathway of complement were detected in 10 of 26 patients with systemic lupus… 
1975
1975
Cleavage of the third complement component (C3) and generation of the spasmogenic peptide, C3a, in human serum via the properdin pathway: demonstration of inhibitory as well as enhancing effects of…
Human and guinea pig serum loses hemolytic activity of the third complement component (C3) during incubation at 37 degrees C. The…