Complement Pathway, Alternative

Known as: complement cascade, alternative pathway, Alternative Complement Pathway, complement activation, alternative pathway 
Complement activation initiated by the interaction of microbial ANTIGENS with COMPLEMENT C3B. When COMPLEMENT FACTOR B binds to the membrane-bound… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Complement alternative pathway plays an important, but not clearly understood, role in neutrophil-mediated diseases. We here show… (More)
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Review
2008
Review
2008
Alternative pathway amplification plays a major role for the final effect of initial specific activation of the classical and… (More)
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Highly Cited
2008
Highly Cited
2008
Dysregulation of the alternative pathway (AP) of complement cascade has been implicated in the pathogenesis of age-related… (More)
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Highly Cited
2006
Highly Cited
2006
Lectin pathway activation of C3 is known to involve target recognition by mannan-binding lectin (MBL) or ficolins and generation… (More)
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Highly Cited
2006
Highly Cited
2006
Neisseria meningitidis binds factor H (fH), a key regulator of the alternative complement pathway. A approximately 29 kD fH… (More)
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Highly Cited
2005
Highly Cited
2005
Age-related macular degeneration (AMD) is the most frequent cause of irreversible blindness in the elderly in developed countries… (More)
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Highly Cited
2003
Highly Cited
2003
The terminal complement components play an important role in mediating tissue injury after ischemia and reperfusion (I/R) injury… (More)
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Highly Cited
1997
Highly Cited
1997
To investigate the role of complement protein factor B (Bf) and alternative pathway activity in vivo, and to test the… (More)
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Highly Cited
1995
Highly Cited
1995
Sea bream serum displayed bactericidal and hemolytic activities. These activities were depleted when serum was incubated with… (More)
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Highly Cited
1988
Highly Cited
1988
Isolated complement components were used to study the regulation of the alternative complement pathway C3 convertase (EC 3.4.21… (More)
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