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Wegener granulomatosis: an analysis of 158 patients.
The course of Wegener granulomatosis has been dramatically improved by daily treatment with cyclophosphamide and glucocorticoids, and has led to increasing concerns about toxicity resulting from prolonged cycloph phosphamide therapy and has encouraged investigation of other therapeutic regimens. Expand
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy.
- T. Chun, L. Stuyver, +6 authors A. Fauci
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 25 November 1997
Highly purified CD4+ T cells from patients receiving HAART with an average treatment time of 10 months and with undetectable plasma viremia carried integrated proviral DNA and were capable of producing infectious virus upon cellular activation in vitro, suggesting persistent active virus replication in vivo. Expand
The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis.
Criteria for the classification of giant cell (temporal) arteritis were developed by comparing 214 patients who had this disease with 593 patients with other forms of vasculitis, and 2 other variables were included: scalp tenderness and claudication of the jaw or tongue or on deglutition. Expand
Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals
- S. Moir, J. Ho, +9 authors A. Fauci
- Biology, Medicine
- The Journal of experimental medicine
- 4 August 2008
HIV-associated premature exhaustion of B cells may contribute to poor antibody responses against HIV in infected individuals, and strikingly, HIV- specific responses were enriched in these exhausted tissuelike memory B cells, whereas total immunoglobulin and influenza-specific responses were enrichment in classical memory B Cells. Expand
Zika Virus in the Americas--Yet Another Arbovirus Threat.
The explosive pandemic of Zika virus infection in South and Central America is the most recent of four unexpected arrivals of important arthropod-borne viral diseases in the Western Hemisphere over… Expand
The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis).
Criteria for the classification of Churg-Strauss syndrome were developed by comparing 20 patients who had this diagnosis with 787 control patients with other forms of vasculitis, and advantages of the traditional format compared with the classification tree format are discussed. Expand
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.
It is shown that long-term remissions can be induced and maintained in an extremely high number of patients by the combination of daily cyclophosphamide and alternate-day prednisone therapy. Expand
The American College of Rheumatology 1990 criteria for the classification of Wegener's granulomatosis.
Criteria for the classification of Wegener's granulomatosis were developed by comparing 85 patients who had this disease with 722 control patients with other forms of vasculitis with a high level of sensitivity and specificity. Expand
Coronavirus Infections-More Than Just the Common Cold.
Yet another pathogenic HCoV, 2019 novel coronavirus (2019-nCoV), was recognized in Wuhan, China, and has caused serious illness and death, and the ultimate scope and effect of this outbreak is unclear at present. Expand
The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis.
Criteria for the classification of Takayasu arteritis were developed by comparing 63 patients who had this disease with 744 control patients with other forms of vasculitis, and the presence of 3 or more of these 6 criteria demonstrated a sensitivity of 90.5% and a specificity of 97.0%. Expand