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Nuclear pore complex glycoproteins contain cytoplasmically disposed O- linked N-acetylglucosamine
A novel form of protein-saccharide linkage consisting of single N- acetylglucosamine (GlcNAc) residues attached in O-linkages directly to the polypeptide backbone has been described (Holt, G. D., andExpand
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The subcellular distribution of terminal N-acetylglucosamine moieties. Localization of a novel protein-saccharide linkage, O-linked GlcNAc.
  • G. Holt, G. Hart
  • Chemistry, Medicine
  • The Journal of biological chemistry
  • 15 June 1986
Previously our laboratory reported the discovery of a novel protein-saccharide linkage in which single N-acetylglucosamine (GlcNAc) residues are attached in O-linkages to protein (Torres, C. R., andExpand
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Serum Troponins as Biomarkers of Drug-Induced Cardiac Toxicity
Member of the Expert Working Group and Chair of the Expert Working Group and Corresponding Author, Professor, Department of Biochemistry & Molecular Biology, University of Minnesota School ofExpand
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Enzymatic addition of O-GlcNAc to nuclear and cytoplasmic proteins. Identification of a uridine diphospho-N-acetylglucosamine:peptide beta-N-acetylglucosaminyltransferase.
An assay for the enzyme responsible for the addition of O-linked N-acetylglucosamine (O-GlcNAc) to proteins, a UDP-N-acetylglucosamine:peptide N-acetylglucosaminyltransferase, is reported using theExpand
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Glycosylation in the nucleus and cytoplasm.
PERSPECTIVES AND SUMMARY 841 BINDING STUDIES USING LECTINS .. .. "........ 843 Lectin Binding Sites in the Nucleus"""""""""" . . """ . . " . . . . " . . " . . """" . . . . . . . 843 Lectin BindingExpand
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Malaria sporozoites and circumsporozoite proteins bind specifically to sulfated glycoconjugates
Circumsporozoite (CS) proteins, which densely coat malaria (Plasmodia) sporozoites, contain an amino acid sequence that is homologous to segments in other proteins which bind specifically to sulfatedExpand
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Properdin binds to sulfatide [Gal(3-SO4)beta 1-1 Cer] and has a sequence homology with other proteins that bind sulfated glycoconjugates.
Properdin, which stabilizes the C3 convertase during the activation of the alternate complement pathway, contains amino acid sequence homologies with several proteins that bind sulfatedExpand
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Abnormal synthesis of dolichol-linked oligosaccharides in carbohydrate-deficient glycoprotein syndrome.
Carbohydrate-deficient glycoprotein syndrome (CDGS) is a rare metabolic disorder presenting in infancy with severe neurologic involvement and variable multisystemic abnormalities. Diagnosis reliesExpand
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Nuclear and cytoplasmic glycosylation: novel saccharide linkages in unexpected places.
Abstract In contrast to all other known forms of protein glycosylation, certain recently described protein-saccharide structures are highly localized to the nucleoplasmic and cytoplasmic compartmentsExpand
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Partial cDNA sequence encoding a nuclear pore protein modified by O-linked N-acetylglucosamine.
The nuclear pore complex contains a family of proteins ranging in molecular mass from 35 to 220 kDa that are glycosylated with O-linked N-acetylglucosamine (GlcNAc) residues. We sought to determineExpand
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