Skip to search formSkip to main contentSkip to account menu

Complement Pathway, Classical

Known as: Classical Complement Activation Pathway, Classical Complement Pathway, Complement Activation Pathway, Classical 
Complement activation initiated by the binding of COMPLEMENT C1 to ANTIGEN-ANTIBODY COMPLEXES at the COMPLEMENT C1Q subunit. This leads to the… 
National Institutes of Health

Related topics

Related topics

14 relations
C1QA wt AlleleC2 wt AlleleC4A wt AlleleC4B wt Allele

Broader (1)

complement pathway

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Blood platelets activate the classical pathway of human complement
Objective: Activation of the complement system plays a key role in inflammation associatedwith vascular injury. Recently… 
Highly Cited
1994
Highly Cited
1994
Mannan-binding protein levels in human amniotic fluid during gestation and its interaction with collectin receptor from amnion cells.
Collectins are a group of soluble proteins, each of which has collagenous and non-collagenous globular domains, and may be… 
Highly Cited
1985
Highly Cited
1985
Influence of genetically inherited complement deficiencies on humoral immune response in guinea pigs.
To assess the role of complement in the induction of the humoral immune response, we studied the antibody response of guinea pigs… 
Highly Cited
1983
Highly Cited
1983
Localization of the membrane attack complex (MAC) in experimental immune complex glomerulonephritis
The role of the membrane attack complex (MAC) as a mediator of renal tissue injury was evaluated in rats affected by bovine serum… 
1982
1982
C4 does not bind to human and rabbit IgM during activation of the classical complement pathway on the red cell.
It has been known for many years that IgG-C4 complexes are generated during the activation of the classical complement pathway… 
1979
1979
Staphylococcus aureus opsonization mediated via the classical and alternative complement pathways. A kinetic study using MgEGTA chelated serum and human sera deficient in IgG and complement factors…
Staphylococcus aureus opsonization was studied kinetically by: (1) determination of the uptake of [3H]-thymidine labelled… 
1977
1977
The cold activation of the classical complement pathway: The cause of the differences between plasma and serum complement in liver cirrhosis.
The mechanism responsible for making the differences between plasma and serum complement (CH50) was studied on eight patients… 
1977
1977
Effect of concanavalin A on the classical complement pathway.
Lysis of sheep erythrocytes (E) sensitized with anti-Forssman antiserum (EA) is inhibited by the action of concanavalin A (Con A… 
1975
1975
C1 fixation and classical complement pathway activation by a fragment of the Cmu4 domain of IgM
A 56 residue fragment derived from a Waldenstrome IgM protein and consisting of 24 residues of the amino-terminal portion of the… 
1973
1973
The reaction of zymosan with the properdin system in normal and C4-deficienct guinea pig serum. Demonstration of C3- and C5-cleaving multi-unit enzymes, both containing factor B, and acceleration of…
On incubation with serum, zymosan (Z) combines with several serum components, collectively designated X, to form an intermediate… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)