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Complement Pathway, Classical

Known as: Classical Complement Activation Pathway, Classical Complement Pathway, Complement Activation Pathway, Classical 
Complement activation initiated by the binding of COMPLEMENT C1 to ANTIGEN-ANTIBODY COMPLEXES at the COMPLEMENT C1Q subunit. This leads to the… 
National Institutes of Health

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14 relations
C1QA wt AlleleC2 wt AlleleC4A wt AlleleC4B wt Allele

Broader (1)

complement pathway

Papers overview

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1995
1995
Collectin in a non-mammalian species: isolation and characterization of mannan-binding protein (MBP) from chicken serum.
A chicken serum lectin was isolated by affinity chromatography on TSK-75 beads derivatized with the monosaccharide N-acetyl-D… 
1986
1986
Repressed classical complement pathway activities and clinical correlations in chronic lymphocytic leukaemia.
Haemolytic activities of the classical and alternative complement pathways, and levels of C1, C4, C3, factor B and C1 inhibitor… 
Highly Cited
1985
Highly Cited
1985
Influence of genetically inherited complement deficiencies on humoral immune response in guinea pigs.
To assess the role of complement in the induction of the humoral immune response, we studied the antibody response of guinea pigs… 
1985
1985
Activation of the human classical complement pathway by a mouse monoclonal hybrid IgG1-2a monovalent anti-TNP antibody bound to TNP-conjugated cells.
A mouse hybridoma selected and cloned for anti-TNP specificity produced three distinct monoclonal antibody species that were… 
1983
1983
Auto-antibody dependent activation of the autologous classical complement pathway by guinea-pig red cells treated with influenza virus or neuraminidase: in vitro and in vivo study.
Guinea-pig erythrocytes that had been exposed to influenza A virus or Vibrio cholerae neuraminidase activated the classical… 
1982
1982
C4 does not bind to human and rabbit IgM during activation of the classical complement pathway on the red cell.
It has been known for many years that IgG-C4 complexes are generated during the activation of the classical complement pathway… 
1977
1977
The cold activation of the classical complement pathway: The cause of the differences between plasma and serum complement in liver cirrhosis.
The mechanism responsible for making the differences between plasma and serum complement (CH50) was studied on eight patients… 
1977
1977
Effect of concanavalin A on the classical complement pathway.
Lysis of sheep erythrocytes (E) sensitized with anti-Forssman antiserum (EA) is inhibited by the action of concanavalin A (Con A… 
1977
1977
Haemolytic assays in agarose plates for components of the classical complement pathway: interference by the alternative pathway.
It has been observed that when serum C6 is measured by the haemolytic radial diffusion technique a heat labile factor limits the… 
1976
1976
Morphological and immunological evidence of coagulopathy in renal complications of pregnancy.
Renal biopsies in 14 patients with P.E.T. or eclampsia showed constant I.F. reactions for IgM and fibrin, with frequent reactions…