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Complement Pathway, Classical

Known as: Classical Complement Activation Pathway, Classical Complement Pathway, Complement Activation Pathway, Classical 
Complement activation initiated by the binding of COMPLEMENT C1 to ANTIGEN-ANTIBODY COMPLEXES at the COMPLEMENT C1Q subunit. This leads to the… 
National Institutes of Health

Related topics

Related topics

14 relations
C1QA wt AlleleC2 wt AlleleC4A wt AlleleC4B wt Allele

Broader (1)

complement pathway

Papers overview

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Highly Cited
1995
Highly Cited
1995
Diversity of Sites for Measles Virus Binding and for Inactivation of Complement C3b and C4b on Membrane Cofactor Protein CD46 (*)
The complement system membrane cofactor protein (MCP) CD46 serves as a C3b/C4b inactivating factor for the protection of host… 
Highly Cited
1995
Highly Cited
1995
A serum mannose-binding lectin mediates complement-dependent lysis of influenza virus-infected cells.
The mechanism of lysis of influenza virus-infected BHK-21 cells by guinea pig serum (GPS) was investigated. Lysis was shown to… 
1995
1995
Circulating levels of mannose binding protein in human immunodeficiency virus infection.
1994
1994
Anti‐complement activity of oleanolic acid: an inhibitor of C3‐convertase of the classical complement pathway
Abstract— Oleanolic acid is a naturally occurring compound, isolated from Luffa cylindrica, which inhibits the in‐vitro immuno… 
1985
1985
Depressed classical complement pathway activities in chronic lymphocytic leukaemia.
Haemolytic activities of the classical and alternative complement pathways, and levels of C1, C4, C3, factor B and C1 inhibitor… 
Highly Cited
1985
Highly Cited
1985
Influence of genetically inherited complement deficiencies on humoral immune response in guinea pigs.
To assess the role of complement in the induction of the humoral immune response, we studied the antibody response of guinea pigs… 
Highly Cited
1984
Highly Cited
1984
Degree of antibody-independent activation of the classical complement pathway by K1 Escherichia coli differs with O antigen type and correlates with virulence of meningitis in newborns
A total of 95 K1 Escherichia coli strains of the O (lipopolysaccharide) serotypes O1, O7, or O18 had been analyzed previously for… 
1983
1983
Deficient Classical Complement Pathway Activity in Newborn Sera
Summary: The bactericidal activity of 20 maternal-neonatal paired sera was assessed employing a clinical type la, group B… 
1977
1977
Activation of the classical complement pathway by Fc fragment of human IgA.
Intact Fcalpha fragments from five human IgA myeloma proteins were produced by two different methods, high temperature… 
1975
1975
C1 fixation and classical complement pathway activation by a fragment of the Cmu4 domain of IgM
A 56 residue fragment derived from a Waldenstrome IgM protein and consisting of 24 residues of the amino-terminal portion of the… 
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