• Publications
  • Influence
Metabolism of ethers in the rabbit. 2. Nuclear-substituted anisoles.
known acid phosphatase and acid pyrophosphatase, a potent alkaline pyrophosphatase, active only in the presence ofadded Mg2+, was found to be present in all vegetable tissues tested. Fresh plantExpand
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Liver carcinomas induced in rats by single administration of dimethylnitrosamine after partial hepatectomy.
  • V. Craddock
  • Medicine
  • Journal of the National Cancer Institute
  • 1 October 1971
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Induction of Liver Cell Adenomata in the Rat by a Single Treatment with N-Methyl-N-Nitrosourea given at Various Times after Partial Hepatectomy
A single treatment of adult animals with the potent carcinogen NMU was known to induce tumours in a wide variety of organs, with the notable exception of liver. Administration of NMU after partialExpand
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Repair and replication of DNA in rat and mouse tissues in relation to cancer induction by N-nitroso-N-alkyl-ureas.
The high susceptibility of certain organs, for example rat brain, to induction of cancer by N-nitroso-N-alkyl-ureas, has been related to a low ability to remove O6-alkylguanine (O6AG) from DNA. It isExpand
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Interactions of testosterone with amino acids.
Abstract The solubility of testosterone in buffered solutions of 18 l -amino acids was determined. In solutions of l -tryptophan, l -tyrosine, l -phenylalanine, l -histidine, l -arginine, and lExpand
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The reaction of N-methyl-N'-nitro-N-nitrosoguanidine with deoxyribonucleic acid.
  • V. Craddock
  • Chemistry, Medicine
  • The Biochemical journal
  • 1 February 1968
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Shortening of life span caused by administration of 5-bromodeoxyuridine to neonatal rats.
  • V. Craddock
  • Biology, Medicine
  • Chemico-biological interactions
  • 1 May 1981
Newborn rats and adult animals in which liver cell replication had been induced by partial hepatectomy were injected with 5-bromodeoxyuridine (BUdR), and were kept without further treatment for theExpand
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Aetiology of oesophageal cancer: some operative factors.
  • V. Craddock
  • Medicine
  • European journal of cancer prevention : the…
  • 1 February 1992
Of the thousands of chemicals tested, the only compounds found to be potent carcinogens for the oesophagus are the N-nitrosamines. Many of these compounds are readily formed from common precursors inExpand
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