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Effects of Extracellular Matrix Components on Axonal Outgrowth from Peripheral Nerves of Adult Animalsin Vitro
Relatively little is known of the growth requirements for regenerating axons of the peripheral nervous system of adult animals. In the present study, we show that extracellular matrix materialExpand
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Matching Strategy and Human Resources in Multinational Corporations
Strategy is implemented by people; this article emphasizes this fundamental notion throughout. The characteristics of the major strategic levels and tasks in a multinational corporation (MNC) areExpand
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Mitogen‐activated protein kinase inhibition reveals differences in signalling pathways activated by neurotrophin‐3 and other growth‐stimulating conditions of adult mouse dorsal root ganglia neurons
PD98059 blocks mitogen‐activated protein kinase (MAPK) by inhibiting its activator, MAP kinase kinase (MEK). We have previously found that PD98059 only transiently inhibits spontaneous axonalExpand
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Temperature effects on fast axonal transport of proteins in vitro in frog sciatic nerves.
A method of studying the fast transport of labeled proteins in frog sciatic nervesin vitro is described. The method, which is a modified procedure of the one previously reported8, makes it possibleExpand
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  • A. Edström
  • Chemistry, Medicine
  • Journal of neurochemistry
  • 1 February 1967
RECENTLY evidence of a local synthesis of acetylcholinesterase in the motor axons of the XIth cranial nerve root was provided by KOENIG (1965a). In previous work (EDSTROM, 1966) the existence of aExpand
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Use of explant cultures of peripheral nerves of adult vertebrates to study axonal regeneration in vitro
Explanted preparations of peripheral nerves with attached dorsal root ganglia of adult mammals and amphibia survive for several days in serum-free medium and can be used to study axonal regenerationExpand
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Role of phosphatidylinositol 3‐kinase in neuronal survival and axonal outgrowth of adult mouse dorsal root ganglia explants
Adult ganglionic peripheral neurons have lost dependence on target‐derived neurotrophin signaling for survival and regeneration after injury. To understand the mechanisms required to sustain suchExpand
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Calmodulin and In Vitro Regenerating Frog Sciatic Nerves: Release and Extracellular Effects
Although calmodulin (CaM) is commonly considered to be an intracellular protein, it has been suggested lately that it is released and exerts functions extracellularly. In the present investigationExpand
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Induction of a sheet polymer of tubulin by Zn2+.
Abstract The in vitro polymerization of bovine brain tubulin in the presence of Zn 2+ has been studied. Zn 2+ , at concentrations higher than 5 × 10 −5 M caused the formation of sheets, sometimesExpand
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