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Carbazilquinone

Known as: Carbazilquinone [Chemical/Ingredient], Carboquinone, 2,5-Cyclohexadiene-1,4-dione, 2-(2-((aminocarbonyl)oxy)-1-methoxyethyl)-3,6-bis(1-aziridinyl)-5-methyl- 
An aziridinylbenzoquinone-based alkylating agent with potential antineoplastic activity. The alkylating group in carboquone becomes activated upon… Expand
National Institutes of Health

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1995
1995
Background. Leukemic transformation of polycythemia vera (PV) and essential thrombocythemia (ET) is influenced by the therapeutic… Expand
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1994
1994
Background. The authors examined the correlation between the expression of glutathione S‐transferase‐pi (GSTπ) and the… Expand
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Highly Cited
1993
Highly Cited
1993
We investigated the applications of back propagation artificial neural networks (ANN) for a small dataset analysis in the field… Expand
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Highly Cited
1987
Highly Cited
1987
The chemosensitivities of 41 poorly differentiated gastric cancer tissues were compared with that of 16 well differentiated… Expand
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1986
1986
A procedure involving direct injection of whole plasma for analyses of drugs by an automated high-performance liquid… Expand
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Highly Cited
1984
Highly Cited
1984
The induction of sister chromatid exchanges (SCE) and mutation at the hypoxanthine-guanine phosphoribosyl transferase locus and… Expand
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Highly Cited
1982
Highly Cited
1982
The generation of hydroxyl free radicals in the system consisting of purified NADPH-cytochrome P-450 reductase and anticancer… Expand
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1980
1980
The effects of treatment with several antitumor agents in combination with hyperthermia (42 degrees and 43 degrees) on the cell… Expand
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Highly Cited
1978
Highly Cited
1978
The mutagenic activities of antitumor agents, including 5 antibiotics, 19 antimetabolites, 5 alkylating agents, 2 alkaloids, 1… Expand
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Highly Cited
1977
Highly Cited
1977
The mode of generation of free radicals of daunomycin, adriamycin, and carboquone in the NADPH-rat liver microsome system was… Expand
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