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Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin
Regulation of the hypothalamic-pituitary-adrenal axis by cytokines: actions and mechanisms of action.
Glucocorticoids are hormone products of the adrenal gland, which have long been recognized to have a profound impact on immunologic processes. The communication between immune and neuroendocrine… Expand
Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin.
Effect of stress on the activity of the hypothalamic-pituitary-gonadal axis: peripheral and central mechanisms.
This article reviews the mechanisms believed to mediate stress-induced inhibition of reproductive functions and the anatomical sites at which these effects take place. Particular emphasis is placed… Expand
Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor.
There is now evidence that the immune system, during times of infectious challenge, can stimulate the secretion of glucocorticoids, the adrenal steroids that mediate important aspects of the response… Expand
Potent, structurally constrained agonists and competitive antagonists of corticotropin-releasing factor.
- József Gulyás, C. Rivier, +7 authors J. Rivier
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 7 November 1995
Predictive methods, physicochemical measurements, and structure activity relationship studies suggest that corticotropin-releasing factor (CRF; corticoliberin), its family members, and competitive… Expand
Corticotropin-Releasing Factor (CRF) and Endocrine Responses to Stress: CRF Receptors, Binding Protein, and Related Peptides
Abstract Corticotropin-releasing factor (CRF) is a 41 -amino acid neuropeptide, which is recognized as a critical mediator of complimentary, stress-related endocrine, autonomic, and behavioral… Expand
Corticotropin-releasing factor: actions on the sympathetic nervous system and metabolism.
- M. Brown, L. Fisher, J. Spiess, C. Rivier, J. Rivier, W. Vale
- Chemistry, Medicine
- 1 September 1982
Corticotropin-releasing factor (CRF) injected into the brains of rats produces hyperglycemia and an increase in plasma concentrations of glucagon, epinephrine, and norepinephrine. Neither… Expand
Chemical and biological characterization of corticotropin releasing factor.
Publisher Summary Hypothalamus liberates a substance into the hypophysial portal blood that stimulates the adrenocorticotrophic hormone (ACTH) activity of the pituitary. This chapter discusses the… Expand
Ontogeny of the stress response in the rat: role of the pituitary and the hypothalamus.
The neonatal rat shows a period of decreased responsiveness to noxious stimuli during the first 3 weeks of life, but the nature of this impairment is still controversial. To test the functionality of… Expand