Embichin
National Institutes of Health
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The elucidation of the mechanism of the cytostatic action of alkylating compounds of the chloralkylamine group still remains an…
: The changes in the molecular weight of DNA one-strand fragments were studied after a short-term incubation of 101/H and CBA…
The changes in the molecular weight of DNA one-strand fragments were studied after a short-term incubation of 101/H and CBA mouse…
The bifunctional and antitumor alkylating agents embichin and its aromatic derivatives sarcolysin and chlorfenacyl remarkably…
Study of embichin binding to human serum albumin in vitro by gel chromatography and fluorescence has shown that embichin is bound…
New methods of radiometry and fractionation of cell lysates on hydroxyapatite were applied to determine the crosslinkage between…
By the use of various methods of deproteinization of chromatin (gel-filtration, ultracentrifugation, chromatography on calcium…
Embichin inhibited the matrix activity of chromatin and DNA in the RNA-polymerase system in vitro much more than its…