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Nitrogen Mustard Compounds

Known as: Nitrogen Mustard Compounds [Chemical/Ingredient], Nitrogen mustards, derivative nitrogen mustard 
A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but… 
National Institutes of Health

Papers overview

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Review
2005
Review
2005
It is a testimony to the complexity of cancer that cytotoxic drugs are still a mainstay of therapeutic approaches to treat that… 
Review
1999
Review
1999
In this overview of the pharmacology of the anticancer drug cyclophosphamide, a brief history of the development of this drug… 
Review
1999
Review
1999
This is primarily an overview of the spontaneous (non-enzymatic) chemistry of the metabolites of cyclophosphamide, viz., cis- and… 
Highly Cited
1988
Highly Cited
1988
Ethacrynic acid and piriprost (6,9-deepoxy-6,9-(phenylimino)-delta 6,8-prostaglandin I1) have been shown to potentiate the… 
Highly Cited
1987
Highly Cited
1987
We have reported previously (C. N. Robson et al., Cancer Res., 46: 6290-6294, 1986) the isolation of a Chinese hamster ovary cell… 
Highly Cited
1986
Highly Cited
1986
Nitrogen mustards alkylate DNA primarily at the N7 position of guanine. Using an approach analogous to that of the Maxam-Gilbert… 
Highly Cited
1981
Highly Cited
1981
Abstract The relationship between DNA cross-linking and cell killing by cis -diamminedichloroplatinum(II) ( cis -DDP) and l… 
Review
1960
Review
1960
Mustard gas [di-(2-chloroethyl) sulphide] and analogous alkylating agents produce a wide range of biological effects (cf. review… 
Highly Cited
1960
Highly Cited
1960
SUMMARY: Thymine-requiring Escherichia coli 15, t– and E. coli B, t– which contained 5-bromouracil in their deoxyribonucleic acid… 
Highly Cited
1955
Highly Cited
1955
Mustard gas (pfl-dichlor-ethyl-sulphide) and its analogues, the nitrogen mustards, are known to be carcinogenic to experimental…