Skip to search formSkip to main contentSkip to account menu

Nitrogen Mustard Compounds

Known as: Nitrogen Mustard Compounds [Chemical/Ingredient], Nitrogen mustards, derivative nitrogen mustard 
A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but… 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (44)

AT 584BO-1051FONP protocolIC 140
EstramustineIn Bloodagonistsantagonists & inhibitors

Broader (1)

haloalkylamine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
Non-covalent ligand/DNA interactions: minor groove binding agents.
Review
1999
Review
1999
An overview of cyclophosphamide development and clinical applications.
In this overview of the pharmacology of the anticancer drug cyclophosphamide, a brief history of the development of this drug… 
Highly Cited
1988
Highly Cited
1988
Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines.
Ethacrynic acid and piriprost (6,9-deepoxy-6,9-(phenylimino)-delta 6,8-prostaglandin I1) have been shown to potentiate the… 
Highly Cited
1987
Highly Cited
1987
Reduced levels of drug-induced DNA cross-linking in nitrogen mustard-resistant Chinese hamster ovary cells expressing elevated glutathione S-transferase activity.
We have reported previously (C. N. Robson et al., Cancer Res., 46: 6290-6294, 1986) the isolation of a Chinese hamster ovary cell… 
Highly Cited
1985
Highly Cited
1985
Increased glutathione-S-transferase activity in a cell line with acquired resistance to nitrogen mustards.
: A Walker 256 rat mammary carcinoma cell line (WR) resistant to bifunctional nitrogen mustards has been shown to have an… 
Review
1960
Review
1960
The reaction of mustard gas with nucleic acids in vitro and in vivo.
Mustard gas [di-(2-chloroethyl) sulphide] and analogous alkylating agents produce a wide range of biological effects (cf. review… 
Highly Cited
1960
Highly Cited
1960
Studies on ultraviolet irradiation of Escherichia coli containing 5-bromouracil in its DNA.
SUMMARY: Thymine-requiring Escherichia coli 15, t– and E. coli B, t– which contained 5-bromouracil in their deoxyribonucleic acid… 
Highly Cited
1955
Highly Cited
1955
Mustard Gas Poisoning, Chronic Bronchitis, and Lung Cancer
Mustard gas (pfl-dichlor-ethyl-sulphide) and its analogues, the nitrogen mustards, are known to be carcinogenic to experimental… 
Review
1953
Review
1953
The chemistry of cytotoxic alkylating agents.
Highly Cited
1947
Highly Cited
1947
Experiences in the Treatment of Neoplastic Disease with Nitrogen Mustard *
The reintroduction of poison gas in warfare by the Germans in 1915 stimulated experimental studies, both in the clinic and in the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)