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Nitrogen Mustard Compounds
Known as:
Nitrogen Mustard Compounds [Chemical/Ingredient]
, Nitrogen mustards
, derivative nitrogen mustard
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A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but…
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National Institutes of Health
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Related topics
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50 relations
Narrower (44)
AT 584
BO-1051
FONP protocol
IC 140
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Estramustine
In Blood
agonists
antagonists & inhibitors
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Broader (1)
haloalkylamine
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
1999
Review
1999
An overview of cyclophosphamide development and clinical applications.
Colvin Om
1999
Corpus ID: 203851683
In this overview of the pharmacology of the anticancer drug cyclophosphamide, a brief history of the development of this drug…
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Highly Cited
1989
Highly Cited
1989
Synthesis of a duplex oligonucleotide containing a nitrogen mustard interstrand DNA-DNA cross-link.
J. Ojwang
,
D. Grueneberg
,
E. Loechler
Cancer Research
1989
Corpus ID: 15203978
Many cancer chemotherapeutic agents react with DNA and give adducts that block DNA replication, which is thought to result in…
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Highly Cited
1988
Highly Cited
1988
Transport, metabolism, and DNA interaction of melphalan in lymphocytes from patients with chronic lymphocytic leukemia.
L. Panasci
,
Derin Henderson
,
San Juana Torres-Garcia
,
V. Skalski
,
S. Caplan
,
Maureen Hutchinson
Cancer Research
1988
Corpus ID: 679456
We investigated the transport of [chloroethyl-14C]melphalan with lymphocytes from three groups of patients with chronic…
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Review
1988
Review
1988
Enzymatic mechanisms of resistance to alkylating agents in tumor cells and normal tissues.
Michael Colvin
,
James E. Russo
,
John Hilton
,
D. Dulik
,
Catherine Fenselau
Advances in Enzyme Regulation
1988
Corpus ID: 5676102
Highly Cited
1970
Highly Cited
1970
Studies on possible mechanisms of programmed cell death in the chick embryo.
D. A. Webster
,
J. Gross
Developmental Biology
1970
Corpus ID: 39675804
Highly Cited
1960
Highly Cited
1960
Studies on ultraviolet irradiation of Escherichia coli containing 5-bromouracil in its DNA.
S. Greer
Journal of General Microbiology
1960
Corpus ID: 9457297
SUMMARY: Thymine-requiring Escherichia coli 15, t– and E. coli B, t– which contained 5-bromouracil in their deoxyribonucleic acid…
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Highly Cited
1952
Highly Cited
1952
Effects of a folic acid antagonist on nucleic acid metabolism.
D. Goldthwait
,
A. Bendich
Journal of Biological Chemistry
1952
Corpus ID: 30402033
Highly Cited
1950
Highly Cited
1950
Chromosome Alteration and Tumour Inhibition by Nitrogen Mustards: the Hypothesis of Cross-linking Alkylation
A. Loveless
,
W. Ross
Nature
1950
Corpus ID: 4200070
IN the foregoing communication, attention is directed to the ability of certain monofunctional alkylating agents to produce…
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Highly Cited
1948
Highly Cited
1948
THE EFFECT OF NITROGEN MUSTARDS ON ENZYMES AND TISSUE METABOLISM
E. S. Guzman Barron
,
G. R. Bartlett
,
Zelma Baker Miller
,
J. Meyer
,
J. E. A_ '~i
,
Seegmiller
Journal of Experimental Medicine
1948
Corpus ID: 24327058
Nitrogen mustards at a concentration forty times the minimum lethal dose inhibited the respiration of all tissues studied but…
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Highly Cited
1947
Highly Cited
1947
Nitrogen mustard therapy in cutaneous blastomatous disease.
Earl D. Osborne
,
J. Jordon
,
Frank C. Hoak
,
Francis J. Pschierer
Journal of the American Medical Association
1947
Corpus ID: 13480045
The paucity of reports in the literature on the use of nitrogen mustard therapy in cutaneous blastomatous disease leads us to…
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