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Fluphenazine

Known as: 2-(Trifluoromethyl)-10-(3-(1-(beta-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine, Fluphenazine [Chemical/Ingredient], 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-(9CI) 
A phenothiazine with antipsychotic activity. Fluphenazine exerts its actions by blocking postsynaptic dopamine D2 receptors in the limbic, cortical… 
National Institutes of Health

Related topics

Related topics

30 relations

Narrower (10)

7-hydroxyfluphenazine7-hydroxyfluphenazine glucuronideFluphenazine HydrochlorideFluphenazine Hydrochloride 5 MG Oral Tablet

Broader (4)

AntiemeticsAntipsychotic AgentsDopamine Antagonistsphenothiazine
Blood Coagulation DisordersBrain Damage, ChronicComatoseDrug Allergy

Papers overview

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Highly Cited
2009
Highly Cited
2009
Determination of phenothiazine derivatives in human urine by using ionic liquid-based dynamic liquid-phase microextraction coupled with liquid chromatography.
Highly Cited
1989
Highly Cited
1989
Possible mechanism of chrysotile asbestos-stimulated superoxide anion production in guinea pig alveolar macrophages.
Highly Cited
1982
Highly Cited
1982
Calcium-dependent protein binding to phenothiazine columns.
Highly Cited
1982
Highly Cited
1982
Dopamine autoreceptor and postsynaptic receptor blocking potency of neuroleptics.
Highly Cited
1981
Highly Cited
1981
Characterisation of the mechanisms by which purported dopamine agonists reduce spontaneous locomotor activity of mice.
Highly Cited
1981
Highly Cited
1981
Inhibition by phenothiazine antipsychotic drugs of calcium-dependent phosphorylation of cerebral cortex proteins regulated by phospholipid or calmodulin.
Highly Cited
1979
Highly Cited
1979
Comparison of the effects of substituted benzamides and standard neuroleptics on the binding of 3H-spiroperidol in the rat pituitary and striatum with in vivo effects on rat prolactin secretion.
Highly Cited
1977
Highly Cited
1977
Characteristics of dopamine and β-adrenergic sensitive adenylate cyclases in the frontal cerebral cortex of the rat. Comparative effects of neuroleptics on frontal cortex and striatal dopamine…
Highly Cited
1976
Highly Cited
1976
Calcium-dependent cyclic nucleotide phosphodiesterase from brain identification of phospholipids as calcium-independent activators.
Highly Cited
1963
Highly Cited
1963
THE SURFACE ACTIVITY OF TRANQUILIZERS.
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