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Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey.
BACKGROUND This study presents estimates of lifetime and 12-month prevalence of 14 DSM-III-R psychiatric disorders from the National Comorbidity Survey, the first survey to administer a structuredExpand
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Biological Insights From 108 Schizophrenia-Associated Genetic Loci
Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of alleles, including common alleles of small effect that might be detected by genome-wide associationExpand
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Genetic epidemiology of major depression: review and meta-analysis.
OBJECTIVE The authors conducted a meta-analysis of relevant data from primary studies of the genetic epidemiology of major depression. METHOD The authors searched MEDLINE and the reference lists ofExpand
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Childhood adversity and adult psychiatric disorder in the US National Comorbidity Survey.
BACKGROUND Survey data are presented on the associations between retrospectively reported childhood adversities and subsequent onset and persistence of DSM-III-R disorders. METHODS Data come fromExpand
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Genome-wide Association Analysis Identifies 14 New Risk Loci for Schizophrenia
Schizophrenia is an idiopathic mental disorder with a heritable component and a substantial public health impact. We conducted a multi-stage genome-wide association study (GWAS) for schizophreniaExpand
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Common variants on chromosome 6p22.1 are associated with schizophrenia
Schizophrenia, a devastating psychiatric disorder, has a prevalence of 0.5–1%, with high heritability (80–85%) and complex transmission. Recent studies implicate rare, large, high-penetrance copyExpand
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Causal relationship between stressful life events and the onset of major depression.
OBJECTIVE Stressful life events are associated with the onset of episodes of major depression. However, exposure to stressful life events is influenced by genetic factors, and these factors areExpand
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Genome-wide association study identifies five new schizophrenia loci
We examined the role of common genetic variation in schizophrenia in a genome-wide association study of substantial size: a stage 1 discovery sample of 21,856 individuals of European ancestry and aExpand
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The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women.
BACKGROUND Patterns of comorbidity suggest that the common psychiatric and substance use syndromes may be divisible into 2 broad groups of internalizing and externalizing disorders. We do not knowExpand
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Specifying race-ethnic differences in risk for psychiatric disorder in a USA national sample.
BACKGROUND Epidemiological studies have found lower than expected prevalence of psychiatric disorders among disadvantaged race-ethnic minority groups in the USA. Recent research shows that this isExpand
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