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Enkephalin, Leucine-2-Alanine
Known as:
DADLE
, Enkephalin, 5-Leucine-2-Alanine
, 5 Leucine 2 Alanine Enkephalin
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A delta-selective opioid (ANALGESICS, OPIOID). It can cause transient depression of mean arterial blood pressure and heart rate.
National Institutes of Health
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11 relations
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BW-180C
dalargin, destyrosyl-
In Blood
Process of secretion
agonists
analogs & derivatives
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Chronic Morphine Treatment Inhibits Opioid Receptor Desensitization and Internalization
Daniela A. Eisinger
,
H. Ammer
,
R. Schulz
Journal of Neuroscience
2002
Corpus ID: 18795496
Chronic opioid receptor (OR) activation by morphine causes distinct cellular adaptations responsible for the development of…
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Highly Cited
2001
Highly Cited
2001
Kappa- but not delta-opioid receptors mediate effects of ischemic preconditioning on both infarct and arrhythmia in rats.
G. Y. Wang
,
S. Wu
,
J. Pei
,
X. Yu
,
T. Wong
American Journal of Physiology. Heart and…
2001
Corpus ID: 27978491
Two series of experiments were performed in the isolated perfused rat heart to determine the role of kappa- and delta-opioid…
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Highly Cited
1998
Highly Cited
1998
Isolation and partial characterization of an opioid-like 88 kDa hibernation-related protein.
N. D. Horton
,
D. Kaftani
,
+8 authors
P. Oeltgen
Comparative Biochemistry and Physiology Part B…
1998
Corpus ID: 24432068
Highly Cited
1986
Highly Cited
1986
Characterization of Opioid Receptors Modulating Noradrenaline Release in the Hippocampus of the Rabbit
R. Jackisch
,
M. Geppert
,
P. Illés
Journal of Neurochemistry
1986
Corpus ID: 19650665
Noradrenaline (NA) release and its modulation via presynaptic opioid receptors were studied in rabbit hippocampal slices, which…
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Highly Cited
1985
Highly Cited
1985
Interaction of Opiates with Opioid Binding Sites in the Bovine Adrenal Medulla: I. Interaction with δ and μ Sites
E. Castanas
,
N. Bourhim
,
P. Giraud
,
F. Boudouresque
,
P. Cantau
,
C. Oliver
1985
Corpus ID: 26080486
Abstract: In the present study we examined the interaction of opiates with the δ and μ opioid binding sites in the bovine adrenal…
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Highly Cited
1982
Highly Cited
1982
Enkephalin-containing neurons in substantia gelatinosa of spinal trigeminal complex: Ultrastructure and synaptic interaction with primary sensory afferents
Khusdev K. Sumal
,
V. Pickel
,
Richard J. Miller
,
D. Reis
Brain Research
1982
Corpus ID: 45132994
Highly Cited
1981
Highly Cited
1981
Effects of [D‐Ala2]‐Methionine‐Enkephalin on Blood Pressure, Heart Rate, and Baroreceptor Reflex Sensitivity in Conscious Cats
T. Yukimura
,
G. Stock
,
H. Stumpf
,
T. Unger
,
D. Ganten
HYPERTENSION
1981
Corpus ID: 99955
SUMMARY Effects of intracerebroventricular (i.c.r.) injection of [D-Ala'1-methionine-enkephalinamide (DAME) on blood pressure (BP…
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Highly Cited
1980
Highly Cited
1980
Substance P- and enkephalin-containing neurones in the rat trigeminal system
M. Fiacco
,
A. Cuello
Neuroscience
1980
Corpus ID: 34273998
Highly Cited
1980
Highly Cited
1980
Post-training intraperitoneal administration of leu-enkephalin and beta-endorphin causes retrograde amnesia for two different tasks in rats.
I. Izquierdo
,
Ant⩽ onio C.M.Paiva
,
E. Elisabetsky
Behavioral and Neural Biology
1980
Corpus ID: 26987710
Highly Cited
1978
Highly Cited
1978
Analgesia by enkephalins injected into the nucleus reticularis gigantocellularis of rat medulla oblongata.
H. Takagi
,
M. Satoh
,
A. Akaike
,
T. Shibata
,
H. Yajima
,
H. Ogawa
European Journal of Pharmacology
1978
Corpus ID: 4549291
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