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Enhancer Elements, Genetic

Known as: Enhancer Element, Enhancer Element, Genetic, Genetic Enhancer Element 
Cis-acting DNA sequences which can increase transcription of genes. Enhancers can usually function in either orientation and at various distances… Expand
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
Master transcription factors Oct4, Sox2, and Nanog bind enhancer elements and recruit Mediator to activate much of the gene… Expand
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Highly Cited
2011
Highly Cited
2011
Chromatin profiling has emerged as a powerful means of genome annotation and detection of regulatory activity. The approach is… Expand
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Highly Cited
2010
Highly Cited
2010
Developmental programs are controlled by transcription factors and chromatin regulators, which maintain specific gene expression… Expand
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Highly Cited
2000
Highly Cited
2000
Plants produce a wide array of natural products, many of which are likely to be useful bioactive structures. Unfortunately, these… Expand
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Highly Cited
1999
Highly Cited
1999
Glucokinase (GK) gene mutations cause diabetes mellitus in both humans and mouse models, but the pathophysiological basis is only… Expand
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Highly Cited
1996
Highly Cited
1996
Hypoxia-inducible factor 1 (HIF-1) is a heterodimeric basic helix-loop-helix transcription factor that regulates hypoxia… Expand
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Highly Cited
1993
Highly Cited
1993
Oxidative stress and expression of the vascular cell adhesion molecule-1 (VCAM-1) on vascular endothelial cells are early… Expand
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Highly Cited
1990
Highly Cited
1990
The promoter region of the interleukin-6 (IL-6) gene has a putative NF-kappa B-binding site. We found that a fragment of the IL-6… Expand
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Highly Cited
1987
Highly Cited
1987
The enhancer-binding protein AP-1 has been purified to greater than 95% homogeneity from HeLa cells by sequence-specific DNA… Expand
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Highly Cited
1986
Highly Cited
1986
To characterize proteins that bind to the immunoglobulin (Ig) heavy chain and the kappa light chain enhancers, an electrophoretic… Expand
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