Regulatory Sequences, Nucleic Acid

Known as: Region, Regulatory, Regulator Regions, Nucleic Acid, Regions, Regulatory 
Any DNA sequence involved in the regulation of genetic processes such as transcription and replication.
National Institutes of Health

Related topics

Related topics

17 relations
ChromosomesDNA-Binding ProteinsNucleotide MotifsRNA Transcription Inhibition
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Narrower (5)

Enhancer Elements, GeneticLocus Control RegionOperator Regions, GeneticPromoter Regions, Genetic
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Broader (1)

Genes

Papers overview

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Highly Cited
2012
Highly Cited
2012
An expansive human regulatory lexicon encoded in transcription factor footprints
Regulatory factor binding to genomic DNA protects the underlying sequence from cleavage by DNase I, leaving nucleotide-resolution… (More)
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Highly Cited
2011
Highly Cited
2011
DNA-binding factors shape the mouse methylome at distal regulatory regions
Methylation of cytosines is an essential epigenetic modification in mammalian genomes, yet the rules that govern methylation… (More)
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Highly Cited
2010
Highly Cited
2010
GREAT improves functional interpretation of cis-regulatory regions
We developed the Genomic Regions Enrichment of Annotations Tool (GREAT) to analyze the functional significance of cis-regulatory… (More)
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Highly Cited
2008
Highly Cited
2008
Alternative Isoform Regulation in Human Tissue Transcriptomes
Through alternative processing of pre-messenger RNAs, individual mammalian genes often produce multiple mRNA and protein isoforms… (More)
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Highly Cited
2001
Highly Cited
2001
GeneMarkS: a self-training method for prediction of gene starts in microbial genomes. Implications for finding sequence motifs in regulatory regions.
Improving the accuracy of prediction of gene starts is one of a few remaining open problems in computer prediction of prokaryotic… (More)
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Review
1998
Review
1998
Understanding adipocyte differentiation.
The adipocyte plays a critical role in energy balance. Adipose tissue growth involves an increase in adipocyte size and the… (More)
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Highly Cited
1998
Highly Cited
1998
Stochastic kinetic analysis of developmental pathway bifurcation in phage lambda-infected Escherichia coli cells.
Fluctuations in rates of gene expression can produce highly erratic time patterns of protein production in individual cells and… (More)
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Highly Cited
1998
Highly Cited
1998
Arabidopsis CBF1 overexpression induces COR genes and enhances freezing tolerance.
Many plants, including Arabidopsis, show increased resistance to freezing after they have been exposed to low nonfreezing… (More)
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Highly Cited
1997
Highly Cited
1997
Arabidopsis thaliana CBF1 encodes an AP2 domain-containing transcriptional activator that binds to the C-repeat/DRE, a cis-acting DNA regulatory element that stimulates transcription in response to…
Recent efforts have defined a cis-acting DNA regulatory element in plants, the C-repeat/dehydration responsive element (DRE… (More)
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Highly Cited
1996
Highly Cited
1996
Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region.
Transporter-facilitated uptake of serotonin (5-hydroxytryptamine or 5-HT) has been implicated in anxiety in humans and animal… (More)
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