Promoter Regions, Genetic
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The human genome contains many thousands of long noncoding RNAs (lncRNAs). While several studies have demonstrated compelling… Expand There is growing recognition that mammalian cells produce many thousands of large intergenic transcripts. However, the functional… Expand This article reviews the mechanisms of gene silencing in cancer and clinical applications of this phenomenon. The silencing of… Expand The character of a cell is defined by its constituent proteins, which are the result of specific patterns of gene expression… Expand Precise mapping of DNA methylation patterns in CpG islands has become essential for understanding diverse biological processes… Expand The bax gene promoter region contains four motifs with homology to consensus p53-binding sites. In cotransfection assays using… Expand The location, orientation, and structure of the hormone regulatory elements (HRE) in nine hormonally modulated genes is described… Expand Although vertebrate DNA is generally depleted in the dinucleotide CpG, it has recently been shown that some vertebrate genes… Expand The DNA sequence of 168 promoter regions (-50 to +10) for Escherichia coli RNA polymerase were compiled. The complete listing was… Expand We constructed a series of recombinant genomes which directed expression of the enzyme chloramphenicol acetyltransferase (CAT) in… Expand