Deoxyribonuclease II

Known as: DNase IIalpha, NUC-1 DNase, deoxyribonuclease IIalpha 
 
National Institutes of Health

Related topics

Related topics

3 relations
APEX1 protein, humanDNASE2 gene

Broader (1)

endodeoxyribonuclease

Papers overview

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2007
2007
Degradation of nuclear DNA by DNase II-like acid DNase in cortical fiber cells of mouse eye lens.
The eye lens is composed of fiber cells that differentiate from epithelial cells on its anterior surface. In concert with this… (More)
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2003
2003
Deoxyribonuclease II is a lysosomal barrier to transfection.
DNA delivered in nonviral vectors or as naked DNA must overcome a number of extracellular and intracellular barriers to… (More)
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Highly Cited
2001
Highly Cited
2001
Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver.
Mature erythrocytes in mammals have no nuclei, although they differentiate from nucleated precursor cells. The mechanism by which… (More)
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Highly Cited
2000
Highly Cited
2000
NUC-1, a caenorhabditis elegans DNase II homolog, functions in an intermediate step of DNA degradation during apoptosis.
One hallmark of apoptosis is the degradation of chromosomal DNA. We cloned the Caenorhabditis elegans gene nuc-1, which is… (More)
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1998
1998
Molecular cloning of the cDNA encoding human deoxyribonuclease II.
A rapid amplification of cDNA ends method, using degenerate oligonucleotides based upon the N-terminal amino acid sequence of… (More)
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1997
1997
Neuronal nitric oxide synthase and calmodulin-dependent protein kinase IIalpha undergo neurotoxin-induced proteolysis.
Calpain (calcium-activated neutral protease) has been implicated as playing a role of neuronal injury in cerebral ischemia and… (More)
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1994
1994
Deoxyribonuclease II in apoptosis and the significance of intracellular acidification.
Many endonucleases have been identified in cells, but which are involved in apoptosis remains controversial. We detected and… (More)
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Highly Cited
1993
Highly Cited
1993
Identification of deoxyribonuclease II as an endonuclease involved in apoptosis.
Cell death occurs by apoptosis during programmed deletion of cells and following exposure to cytotoxic agents. Central to the… (More)
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1986
1986
Chromatin binding of epidermal growth factor, nerve growth factor, and platelet-derived growth factor in cells bearing the appropriate surface receptors.
We analyzed the uptake and intracellular distribution of 125I-labeled epidermal growth factor, nerve growth factor, and platelet… (More)
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1984
1984
DNA structural variations in the E. coli tyrT promoter.
X-ray studies have established that the structure of a right-handed, Watson-Crick double helix can change from place to place… (More)
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