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Conservation of the Notch signalling pathway in mammalian neurogenesis.
Conservation of the Notch pathway and its regulatory mechanisms from fly to mouse are demonstrated, and a role for the murine Notch signalling pathway in the regulation of neural stem cell differentiation is supported.
DNase II: genes, enzymes and function.
Transport of Zn in a sandy loam soil treated with ZnO NPs and uptake by corn plants: Electron microprobe and confocal microscopy studies
Effect of surface coating and organic matter on the uptake of CeO2 NPs by corn plants grown in soil: Insight into the uptake mechanism.
Regulation of the RAG-1 promoter by the NF-Y transcription factor.
- S. Brown, G. A. Miranda, Z. Galic, I. Hartman, C. Lyon, R. Aguilera
- BiologyJournal of immunology
- 1 June 1997
We have cloned the RAG-1 promoter region and have determined that almost all detectable promoter activity resides within a 208-bp fragment. Sequence analysis of this promoter region has identified…
DNase II deficiency impairs innate immune function in Drosophila.
Structure of acid deoxyribonuclease
- Armando Varela-Ramírez, J. Abendroth, R. Aguilera
- Chemistry, BiologyNucleic acids research
- 29 March 2017
It is demonstrated that recombinant Burkholderia thailandensis DNase II is highly active at low pH in the absence of divalent metal ions, similar to eukaryoticDNase II.
Titanocene-phosphine derivatives as precursors to cytotoxic heterometallic TiAu2 and TiM (M = Pd, Pt) compounds. Studies of their interactions with DNA.
A series of tri- and bimetallic titanium-gold, titanium-palladium, and titanium-platinum derivatives of the general formulas have been synthesized and characterized by different spectroscopic techniques and mass spectrometry, and all of these complexes show a stronger interaction with DNA than that displayed by Cp (2)TiCl(2) at neutral pH.
Recombinant human lactoferrin induces apoptosis, disruption of F-actin structure and cell cycle arrest with selective cytotoxicity on human triple negative breast cancer cells
- Blanca F Iglesias-Figueroa, T. Siqueiros-Cendón, Q. Rascón-Cruz
- Biology, ChemistryApoptosis
- 1 August 2019
Overall results suggest that rhLf is using the apoptosis pathway as its mechanism to inflict cell death on triple-negative breast cancer MDA-MB-231 cells, suggesting further evaluation ofrhLf as a potential anti-breast cancer drug option.
Searching in Mother Nature for Anti-Cancer Activity: Anti-Proliferative and Pro-Apoptotic Effect Elicited by Green Barley on Leukemia/Lymphoma Cells
Green barley extract has potential as an anti-leukemia/lymphoma agent alone or in combination with standard cancer therapies and thus warrants further evaluation in vivo to support these findings.