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Cyclic AMP-Dependent Protein Kinases

Known as: cAMP Dependent Protein Kinase, Protein Kinase A, Cyclic AMP Dependent Protein Kinase 
Most cellular effects of cAMP are mediated through PKA by serine or threonine phosphorylation of target proteins. Human Protein Kinase A (cAMP Ser… 
National Institutes of Health

Related topics

Related topics

24 relations
A Kinase Anchor ProteinsIn BloodPRKACA protein, humanPRKACB protein, human

Broader (2)

PhosphotransferasesProtein-Serine-Threonine Kinases

Narrower (3)

PkaB protein, Aspergillus nidulansTPK2 protein, S cerevisiaecAMP-dependent protein kinase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling.
Hedgehogs (Hhs) are key signaling regulators of stem cell maintenance and tissue patterning in embryos, and activating mutations… 
Highly Cited
2006
Highly Cited
2006
Paracrine and autocrine regulation of epidermal growth factor-like factors in cumulus oocyte complexes and granulosa cells: key roles for prostaglandin synthase 2 and progesterone receptor.
The molecular bridges that link the LH surge with functional changes in cumulus cells that possess few LH receptors are being… 
Review
2003
Review
2003
Regulation of the osteoblast‐specific transcription factor, Runx2: Responsiveness to multiple signal transduction pathways
The Cbfa1/Runx2 is an important transcription factor necessary for osteoblast differentiation and bone formation. However, the… 
Highly Cited
2002
Highly Cited
2002
Proteolysis of the Hedgehog Signaling Effector Cubitus interruptus Requires Phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1
Review
2000
Review
2000
Regulation of Cardiac L-Type Calcium Channels by Protein Kinase A and Protein Kinase C
Abstract— Voltage-dependent L-type Ca2+ channels are multisubunit transmembrane proteins, which allow the influx of Ca2+ (ICa… 
Review
2000
Review
2000
Transcriptional mechanisms of chondrocyte differentiation.
Highly Cited
1998
Highly Cited
1998
Different training procedures recruit either one or two critical periods for contextual memory consolidation, each of which requires protein synthesis and PKA.
We have used a combined genetic and pharmacological approach to define the time course of the requirement for protein kinase A… 
Highly Cited
1998
Highly Cited
1998
Modulation of TTX-R INa by PKC and PKA and Their Role in PGE2-Induced Sensitization of Rat Sensory Neurons In Vitro
A tetrodotoxin-resistant voltage-gated Na+current (TTX-R INa) appears to be the current primarily responsible for action… 
Highly Cited
1996
Highly Cited
1996
Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes.
We have observed that stimulation of human natural killer cells with dibutyryl cAMP (Bt2cAMP) reproduced the effects of ADP… 
Highly Cited
1993
Highly Cited
1993
Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation
Cyclic AMP (cAMP)-dependent protein kinase A (PKA) stimulates the transcription of many eucaryotic genes by catalyzing the… 
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