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Protein-Serine-Threonine Kinases

Known as: Serine-Threonine Protein Kinases, Kinase, Protein-Serine, Kinase, Threonine 
A class of enzymes that transfer phosphate groups to serine or threonine residues in peptides or proteins. These proteins are involved in the… 
National Institutes of Health

Related topics

Related topics

49 relations
BCR protein, humanBRAF protein, humanCell Cycle ProteinsEnzyme Gene

Narrower (38)

CDC28 Protein Kinase, S cerevisiaeCDK2 protein, humanCERK1 protein, ArabidopsisCol4a3bp protein, mouse

Papers overview

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Highly Cited
2006
Highly Cited
2006
MAPKAP Kinase 2-Deficient Mice Are Resistant to Collagen-Induced Arthritis
TNF-α is a pleiotropic cytokine considered a primary mediator of immune regulation and inflammatory response and has been shown… 
Highly Cited
2002
Highly Cited
2002
Evidence that a eukaryotic-type serine/threonine protein kinase from Mycobacterium tuberculosis regulates morphological changes associated with cell division.
A eukaryotic-type protein serine/threonine kinase, PknA, was cloned from Mycobacterium tuberculosis strain H37Ra. Sequencing of… 
Highly Cited
2002
Highly Cited
2002
Akt (Protein Kinase B) Negatively Regulates SEK1 by Means of Protein Phosphorylation*
The protein serine-threonine kinase Akt mediates cell survival signaling initiated by various growth-promoting factors such as… 
Highly Cited
2001
Highly Cited
2001
Linking molecular therapeutics to molecular diagnostics: Inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo
Molecular therapeutics, targeting the underlying defects leading to cancer initiation and progression, are the “holy grail” of… 
Highly Cited
1998
Highly Cited
1998
Cloning and characterization of Dlk, a novel serine/threonine kinase that is tightly associated with chromatin and phosphorylates core histones
We cloned a cDNA coding for a novel serine/threonine kinase, Dlk, a protein of 448 amino acids with a predicted molecular weight… 
Highly Cited
1993
Highly Cited
1993
The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2.
The substrate specificity of mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MAPKAP kinase-2) was investigated… 
Highly Cited
1991
Highly Cited
1991
Fibroblast growth factor receptors from liver vary in three structural domains.
Changes in heparin-binding fibroblast growth factor gene expression and receptor phenotype occur during liver regeneration and in… 
Highly Cited
1989
Highly Cited
1989
Direct activation of the serine/threonine kinase activity of raf-1 through tyrosine phosphorylation by the PDGF β-receptor
Highly Cited
1987
Highly Cited
1987
Homology probing: identification of cDNA clones encoding members of the protein-serine kinase family.
Mixed oligonucleotide probes were used to screen a HeLa cDNA library for clones encoding amino acid contiguities whose… 
Highly Cited
1972
Highly Cited
1972
Rat brain microtubule protein: purification and determination of covalently bound phosphate and carbohydrate.
Microtubule protein purified from rat brain by published procedures contains nucleic acid and carbohydrate contaminants… 
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