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Protein-Serine-Threonine Kinases

Known as: Serine-Threonine Protein Kinases, Kinase, Protein-Serine, Kinase, Threonine 
A class of enzymes that transfer phosphate groups to serine or threonine residues in peptides or proteins. These proteins are involved in the… 
National Institutes of Health

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Papers overview

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Review
2007
Review
2007
AKT/PKB Signaling: Navigating Downstream
Highly Cited
1999
Highly Cited
1999
NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase
Activation of the nuclear transcription factor NF-κB by inflammatory cytokines requires the successive action of NF-κB-inducing… 
Highly Cited
1999
Highly Cited
1999
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
Highly Cited
1998
Highly Cited
1998
A serine/threonine kinase gene defective in Peutz–Jeghers syndrome
Studies of hereditary cancer syndromes have contributed greatly to our understanding of molecular events involved in… 
Highly Cited
1997
Highly Cited
1997
Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt
A signaling pathway was delineated by which insulin-like growth factor 1 (IGF-1) promotes the survival of cerebellar neurons. IGF… 
Highly Cited
1997
Highly Cited
1997
Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery
Highly Cited
1997
Highly Cited
1997
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt.
BAD is a distant member of the Bcl-2 family that promotes cell death. Phosphorylation of BAD prevents this. BAD phosphorylation… 
Highly Cited
1995
Highly Cited
1995
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
A serine/threonine kinase, named protein kinase B (PKB)1 for its sequence homology to both protein kinase A and C, has previously… 
Highly Cited
1994
Highly Cited
1994
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
A new brain serine/threonine protein kinase may be a target for the p21 ras -related proteins Cdc42 and Rac1. The kinase sequence… 
Highly Cited
1991
Highly Cited
1991
A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region.
The v-akt oncogene codes for a 105-kilodalton fusion phosphoprotein containing Gag sequences at its amino terminus. Sequence… 
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