CDK2 protein, human

Known as: Cell Division Protein Kinase 2, CDK2, p33(CDK2) 
Cyclin-dependent kinase 2 (298 aa, ~34 kDa) is encoded by the human CDK2 gene. This protein is involved in the regulation of both phosphorylation of… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Most RNAs generated by the human genome have no protein-coding ability and are termed non-coding RNAs. Among these include… (More)
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Tissue homeostasis in metazoans is regulated by transitions of cells between quiescence and proliferation. The hallmark of… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
The function of cyclin-dependent kinase 2 (CDK2) is often abolished after DNA damage. The inhibition of CDK2 plays a central role… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The genomic organization of the CDK2 gene, which overlaps the melanocyte-specific gene SILV/PMEL17, poses an interesting… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
We have investigated the contribution of CDK4 and CDK2 inhibition to G1 arrest in colon cancers following inhibition of the MEK… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Cyclin-dependent kinases (CDKs) are essential for regulating key transitions in the cell cycle, including initiation of DNA… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
CDK inhibitors are thought to prevent cell proliferation by negatively regulating cyclin-CDK complexes. We propose that the… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Most nonmalignant cells are anchorage-dependent; they require substrate attachment for growth and, in some instances, survival… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
E2F-1, a member of the E2F transcription factor family, contributes to the regulation of the G1-to-S phase transition in higher… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
We have examined the role of phosphorylation in the regulation of human cyclin-dependent kinase-2 (CDK2), a protein closely… (More)
Is this relevant?