The Molecular Biology of Memory Storage: A Dialogue Between Genes and Synapses
- E. Kandel
- Biology, PsychologyScience
- 2 November 2001
This book aims to investigate elementary forms of learning and memory at a cellular molecular level—as specific molecular activities within identified nerve cells withinidentified nerve cells.
Control of Memory Formation Through Regulated Expression of a CaMKII Transgene
- M. Mayford, M. Bach, Yan-You Huang, Lei Wang, R. Hawkins, E. Kandel
- Biology, PsychologyScience
- 6 December 1996
A forebrain-specific promoter was combined with the tetracycline transactivator system to achieve both regional and temporal control of transgene expression, and the CaMKII signaling pathway is critical for both explicit and implicit memory storage.
Recombinant BDNF Rescues Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice
- S. Patterson, T. Abel, T. A. Deuel, K. Martin, Jack C Rose, E. Kandel
- BiologyNeuron
- 1 June 1996
Resolving Emotional Conflict: A Role for the Rostral Anterior Cingulate Cortex in Modulating Activity in the Amygdala
- A. Etkin, T. Egner, Daniel M. Peraza, E. Kandel, J. Hirsch
- Psychology, BiologyNeuron
- 21 September 2006
Chromatin Acetylation, Memory, and LTP Are Impaired in CBP+/− Mice A Model for the Cognitive Deficit in Rubinstein-Taybi Syndrome and Its Amelioration
- J. Alarcon, G. Malleret, A. Barco
- BiologyNeuron
- 24 June 2004
Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain
- J. Tsien, D. Chen, S. Tonegawa
- BiologyCell
- 27 December 1996
Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons.
Activation of PKA may be a component of the mechanism that generates L-LTP, and analogs of cAMP induced a potentiation that blocked naturally induced L- LTP, which was blocked by inhibitors of protein synthesis.
Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus
- M. Saxe, F. Battaglia, M. Drew
- Biology, PsychologyProceedings of the National Academy of Sciences
- 14 November 2006
The findings show that adult-born neurons make a distinct contribution to some but not all hippocampal functions and show that new hippocampal neurons can be preferentially recruited over mature granule cells in vitro and may provide a framework for how this small cell population can influence behavior.
Genetic Demonstration of a Role for PKA in the Late Phase of LTP and in Hippocampus-Based Long-Term Memory
- T. Abel, P. Nguyen, M. Barad, T. A. Deuel, E. Kandel, R. Bourtchouladze
- Biology, PsychologyCell
- 7 March 1997
Proceedings of the National Academy of Sciences of the United States of America. Annual subject and author indexes.
- H. Secretary, J. Wyngaarden, D. Koshland
- HistoryProceedings of the National Academy of Sciences…
- 1990
This dissertation aims to provide a history of web exceptionalism from 1989 to 2002, a period chosen in order to explore its roots as well as specific cases up to and including the year in which descriptions of “Web 2.0” began to circulate.
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