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CD80 gene

Known as: CD80 ANTIGEN, CD80 Molecule Gene, CD28 ANTIGEN LIGAND 1 
This gene is involved in the stimulation of T-cells and in immune responses.
National Institutes of Health

Related topics

Related topics

9 relations
CD80 AntigensCell AdhesionIntercellular Communication ProcessLigand Binding

Narrower (1)

CD80 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
B7 Costimulation Molecules Expressed from the Herpes Simplex Virus 2 Genome Rescue Immune Induction in B7-Deficient Mice
ABSTRACT The interaction between B7 costimulation molecules on antigen-presenting cells and CD28 on antigen-responsive T cells is… 
Highly Cited
2001
Highly Cited
2001
CD28-independent Costimulation of T Cells in Alloimmune Responses1
T cell costimulation by B7 molecules plays an important role in the regulation of alloimmune responses. Although both B7-1 and B7… 
1999
1999
Effects of anti-B7 monoclonal antibodies on humoral immune responses.
The costimulatory interaction between CD28 on T cells and B7-related molecules on antigen presenting cells plays an important… 
1998
1998
Distinct roles for B7 costimulation in contact hypersensitivity and humoral immune responses to epicutaneous antigen
Productive interactions between B7‐1 and B7‐2 costimulatory molecules on dendritic cells (DC) and CD28 on T cells are thought to… 
Highly Cited
1998
Highly Cited
1998
High-Efficiency Gene Transfer into Normal and Adenosine Deaminase-Deficient T Lymphocytes Is Mediated by Transduction on Recombinant Fibronectin Fragments
ABSTRACT Primary human T lymphocytes are powerful targets for genetic modification, although the use of these targets in human… 
Highly Cited
1997
Highly Cited
1997
B7‐1‐dependent co‐stimulation results in qualitatively and quantitatively different responses by CD4+ and CD8+ T cells
To characterize better the co‐stimulatory activity of native B7‐1 in the absence of other receptor/ligand interactions that might… 
Highly Cited
1996
Highly Cited
1996
Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection.
Recent data implicates a role for the CD40-CD40 ligand (CD40L) pathway in graft rejection. One potential mechanism is direct… 
Highly Cited
1996
Highly Cited
1996
B7-2 (CD86) is essential for the development of IL-4-producing T cells.
The CD28/CTLA-4 ligands, B7-1 (CD80) and B7-2 (CD86), provide a co-stimulatory signal necessary for optimal T cell activation. We… 
Highly Cited
1995
Highly Cited
1995
Reciprocal expression of co‐stimulatory molecules, B7‐1 and B7‐2, on murine T cells following activation
The co‐stimulatory B7 molecules (B7‐1 and B7‐2) are expressed on professional antigen‐presenting cells in mice. In this study, we… 
Highly Cited
1994
Highly Cited
1994
A negative regulatory function of B7 revealed in B7-1 transgenic mice.
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