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- Dianne L. Chambless, William C. Sanderson, +9 authors David A. Williams
- 1998
Dianne L. Chambless, William C. Sanderson, Varda Shoham, Suzanne Bennett Johnson, Kenneth S. Pope, Paul Crits-Christoph, Mary Baker, Benjamin Johnson, Sheila R. Woody, Stanley Sue, Larry Beutler,… (More)
- Jonathan D. Pollock, David A. Williams, +6 authors Mary Dinauer
- Nature Genetics
- 1995
Chronic granulomatous disease (CGD) is a recessive disorder characterized by a defective phagocyte respiratory burst oxidase, life–threatening pyogenic infections and inflammatory granulomas. Gene… (More)
- Charles E. Murry, Mark H. Soonpaa, +11 authors Loren J. Field
- Nature
- 2004
The mammalian heart has a very limited regenerative capacity and, hence, heals by scar formation. Recent reports suggest that haematopoietic stem cells can transdifferentiate into unexpected… (More)
- Thorsten Giesecke, Richard H. Gracely, +4 authors Daniel J. Clauw
- Arthritis and rheumatism
- 2004
OBJECTIVE
For many individuals with chronic low back pain (CLBP), there is no identifiable cause. In other idiopathic chronic pain conditions, sensory testing and functional magnetic resonance… (More)
- Yi Gu, M. C. Filippi, +9 authors David A. Williams
- Science
- 2003
The Rho guanosine triphosphatases (GTPases) Rac1 and Rac2 are critical signaling regulators in mammalian cells. The deletion of both Rac1 and Rac2 murine alleles leads to a massive egress of… (More)
Canonical Wnt signaling critically regulates cell fate and proliferation in development and disease. Nuclear localization of beta-catenin is indispensable for canonical Wnt signaling; however, the… (More)
- Ronald Greeley, B. H. Foing, +6 authors Tanja E. Zegers
- 2005
[1] Rocks on the floor of Gusev crater are basaltic in composition, as determined from measurements by the Mars Exploration Rover, Spirit. On the basis of compositional data, models of the basaltic… (More)
- Marita J Walmsley, Steen K. T. Ooi, +7 authors Victor L. J. Tybulewicz
- Science
- 2003
The Rac1 guanosine triphosphatase (GTPase) has been implicated in multiple cellular functions, including actin dynamics, proliferation, apoptosis, adhesion, and migration resulting from signaling by… (More)
- Mastura Monif, Christopher A. Reid, Kim L. Powell, Megan L Smart, David A. Williams
- The Journal of neuroscience : the official…
- 2009
Microglial activation is an integral part of neuroinflammation associated with many neurodegenerative conditions. Interestingly, a number of neurodegenerative conditions exhibit enhanced P2X(7)… (More)
- Louise A. Harkin, David N. Bowser, +9 authors Steven Petrou
- American journal of human genetics
- 2002
Recent findings from studies of two families have shown that mutations in the GABA(A)-receptor gamma2 subunit are associated with generalized epilepsies and febrile seizures. Here we describe a… (More)