Skip to search formSkip to main contentSkip to account menu

CD80 wt Allele

Known as: CD80 Antigen (CD28 Antigen Ligand 1, B7-1 Antigen) Gene, CD28LG, LAB7 
Human CD80 wild-type allele is located within 3q13.3-q21 and is approximately 35 kb in length. This allele, which encodes T-lymphocyte activation… 
National Institutes of Health

Related topics

Related topics

11 relations
3q13.3-q21CD80 AntigensCell AdhesionIntercellular Communication Process

Broader (1)

CD80 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Stromal cells’ B7‐1 is a key stimulatory molecule for interleukin‐10 production by HOZOT, a multifunctional regulatory T‐cell line
We have previously shown that xenogeneic stromal cell stimulation of naïve T cells resulted in the generation of a new type of… 
2000
2000
Gene transfer to liver cancer cells of B7-1 plus interleukin 12 changes immunoeffector mechanisms and suppresses helper T cell type 1 cytokine production induced by interleukin 12 alone.
To investigate the cooperative effect of B7-1 and IL-12 in the induction of antitumor activity, we have developed retroviral… 
2000
2000
Cancer Vaccination by B7-1-Transfected Hepatocellular Carcinoma Cells
Human hepatocellular carcinoma (HCC), one of the most common cancers, frequently recurs after primary therapy. A way to prevent… 
Highly Cited
1999
Highly Cited
1999
Expression and contribution of B7-1 (CD80) and B7-2 (CD86) in the early immune response to Leishmania major infection.
CD28 interactions promote T cell responses, and whether B7-1 or B7-2 is utilized may influence Th cell subset development. CD28… 
Highly Cited
1997
Highly Cited
1997
A Leishmania protein that modulates interleukin (IL)‐12, IL‐10 and tumor necrosis factor‐α production and expression of B7‐1 in human monocyte‐derived antigen‐presenting cells
LeIF, a gene homologue of the eukaryotic initiation factor 4A was first described as a leishmanial antigen that induced a Th1… 
Highly Cited
1997
Highly Cited
1997
Expression of costimulatory molecules B7‐1 (CD80) and B7‐2 (CD86) on human hepatocellular carcinoma
Costimulation mediated by costimulatory molecules, such as B7‐1 and B7‐2, which are ligands for the CD28/cytolytic T lymphocyte… 
Highly Cited
1997
Highly Cited
1997
B7‐1‐dependent co‐stimulation results in qualitatively and quantitatively different responses by CD4+ and CD8+ T cells
To characterize better the co‐stimulatory activity of native B7‐1 in the absence of other receptor/ligand interactions that might… 
Highly Cited
1995
Highly Cited
1995
Costimulation with B7-1, IL-6, and IL-12 is sufficient for primary generation of murine antitumor cytolytic T lymphocytes in vitro.
The requirements for generating CD8+ CTLs against the mastocytoma P815 were first defined by using an allogeneic mixed lymphocyte… 
Highly Cited
1995
Highly Cited
1995
Both CD28 ligands CD80 (B7-1) and CD86 (B7-2) activate phosphatidylinositol 3-kinase, and wortmannin reveals heterogeneity in the regulation of T cell IL-2 secretion.
In this report, the co-stimulatory signals provided by CD80 (B7-1) or CD86 (B7-2) were compared to CD28 ligation by mAb. We… 
Highly Cited
1994
Highly Cited
1994
IL-4 treatment of small splenic B cells induces costimulatory molecules B7-1 and B7-2.
IL-4 has been shown to be involved in the early stages of B cell maturation. Changes induced by IL-4 include cell enlargement… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)