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CD80 Antigens

Known as: B Cell Activation Antigen, B7 1 Costimulatory Molecule, B7-1 Antigen 
A costimulatory ligand expressed by ANTIGEN-PRESENTING CELLS that binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Myeloid-derived suppressor cells (MDSC) have emerged as key immune modulators in various tumor models and human malignancies, but… Expand
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Highly Cited
2007
Highly Cited
2007
To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic… Expand
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Highly Cited
2006
Highly Cited
2006
An elevated number of Gr-1+CD11b+ myeloid cells has been described in mice bearing transplantable tumors, and has been associated… Expand
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Highly Cited
2004
Highly Cited
2004
Regulatory T cells (Treg) are important in maintaining tolerance to self tissues. As both CD28 and CTLA-4 molecules are… Expand
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Review
2003
Review
2003
CD28 and CD152 have crucial yet opposing functions in T-cell stimulation, in which CD28 promotes but CD152 inhibits T-cell… Expand
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Highly Cited
1997
Highly Cited
1997
The structurally related T cell surface molecules CD28 and CTLA-4 interact with cell surface ligands CD80 (B7-1) and CD86 (B7-2… Expand
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Highly Cited
1996
Highly Cited
1996
Recent data implicates a role for the CD40-CD40 ligand (CD40L) pathway in graft rejection. One potential mechanism is direct… Expand
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Highly Cited
1995
Highly Cited
1995
Signals initiated through both the TCR complex and CD28 are required for optimal activation of T lymphocytes. Recently, it has… Expand
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Highly Cited
1994
Highly Cited
1994
B7-0 or B7-2 (CD86) is a T cell costimulatory molecule that binds the same receptors (CD28 and CTLA-4) as B7-1 (CD80), but shares… Expand
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Highly Cited
1994
Highly Cited
1994
Dendritic cells, the professional antigen-presenting cells (APC) involved in T cell priming, express CD40, a molecule which… Expand
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