Skip to search formSkip to main contentSkip to account menu

CD86 Antigen

Known as: Antigen, CD86, Antigens, CD86 [Chemical/Ingredient], CD86 Antigens 
A costimulatory ligand expressed by ANTIGEN-PRESENTING CELLS that binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low… 
National Institutes of Health

Related topics

Related topics

15 relations

Broader (2)

CD80 AntigensMembrane Glycoproteins
CD86 geneImmunoglobulin DomainsIn BloodProcess of secretion

Narrower (1)

Cd86 protein, rat

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Reciprocal activating interaction between dendritic cells and pamidronate-stimulated gammadelta T cells: role of CD86 and inflammatory cytokines.
We investigated the interactions between human monocyte-derived dendritic cells (DCs) and Ag-activated circulating TCR-gammadelta… 
Highly Cited
2003
Highly Cited
2003
Natural Alpha Interferon-Producing Cells Respond to Human Immunodeficiency Virus Type 1 with Alpha Interferon Production and Maturation into Dendritic Cells
ABSTRACT Natural alpha interferon (IFN-α)-producing cells (IPCs) are now recognized as identical to plasmacytoid dendritic cell… 
Highly Cited
2002
Highly Cited
2002
When ligand becomes receptor—tolerance via B7 signaling on DCs
CTLA-4–Ig is used to block the costimulation of T cells to interfere with their activation. This reagent may actually be working… 
Highly Cited
2001
Highly Cited
2001
INDUCTION THERAPY WITH MONOCLONAL ANTIBODIES SPECIFIC FOR CD80 AND CD86 DELAYS THE ONSET OF ACUTE RENAL ALLOGRAFT REJECTION IN NON-HUMAN PRIMATES1
CD80 and CD86 (also known as B7–1 and B7–2, respectively) are both ligands for the T cell costimulatory receptors CD28 and CD152… 
Highly Cited
2001
Highly Cited
2001
Activating Immunity in the Liver. I. Liver Dendritic Cells (but Not Hepatocytes) Are Potent Activators of IFN-γ Release by Liver NKT Cells1
A prominent subset of the hepatic innate immune system is α-galactosylceramide (αGalCer)-reactive, (CD4+ and CD4−CD8−) CD1d… 
Highly Cited
2000
Highly Cited
2000
Intratumoral injection of dendritic cells derived in vitro in patients with metastatic cancer
Dendritic cells (DCs) are potent initiators of immune responses, and the infiltration of DCs into tumors may confer an improved… 
Highly Cited
1999
Highly Cited
1999
Depletion in blood CD11c-positive dendritic cells from HIV-infected patients.
OBJECTIVES To quantify blood dendritic cells from HIV-positive patients and to study the expression of functional molecules, in… 
Highly Cited
1999
Highly Cited
1999
Human lung dendritic cells have an immature phenotype with efficient mannose receptors.
Dendritic cells (DC) can be present at distinct stages of differentiation within the immune system. Sallusto and colleagues have… 
Highly Cited
1999
Highly Cited
1999
Modulation of the activity of human monocyte-derived dendritic cells by chemical haptens, a metal allergen, and a staphylococcal superantigen.
For the development of mechanistic assays in immunotoxicology, the phenotype, cytokine production, and stimulatory function of… 
Highly Cited
1996
Highly Cited
1996
B7-2 (CD86) is essential for the development of IL-4-producing T cells.
The CD28/CTLA-4 ligands, B7-1 (CD80) and B7-2 (CD86), provide a co-stimulatory signal necessary for optimal T cell activation. We… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)