CD86 gene

Known as: B-lymphocyte antigen B7-2, CD86 molecule, CD28 ANTIGEN LIGAND 2 
This gene plays a role in the modulation of T-cell proliferation and interleukin production.

Topic mentions per year

Topic mentions per year

1988-2017
05010019882017

Papers overview

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Highly Cited
2005
Highly Cited
2005
Exosomes are secreted vesicles formed in late endocytic compartments. Immature dendritic cells (DCs) secrete exosomes, which… (More)
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Highly Cited
2002
Highly Cited
2002
B7-1 and B7-2 are generally thought to have comparable structures and affinities for their receptors, CD28 and CTLA-4, each of… (More)
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Highly Cited
1999
Highly Cited
1999
In a screen to identify genes induced by NF-kappaB/Rel transcription factors, we cloned a novel gene, b7h, that is a close… (More)
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Highly Cited
1997
Highly Cited
1997
Increasing evidence supports involvement of inflammation and immunity in atherogenesis. We report here that CD40 ligand (CD40L… (More)
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Highly Cited
1995
Highly Cited
1995
Signals initiated through both the TCR complex and CD28 are required for optimal activation of T lymphocytes. Recently, it has… (More)
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Highly Cited
1995
Highly Cited
1995
Insulin-dependent diabetes mellitus (IDDM) is thought to be an immunologically mediated disease resulting in the complete… (More)
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Highly Cited
1995
Highly Cited
1995
Costimulatory interactions between T and B lymphocytes are crucial for T cell activation and B cell proliferation and… (More)
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Highly Cited
1994
Highly Cited
1994
B7-0 or B7-2 (CD86) is a T cell costimulatory molecule that binds the same receptors (CD28 and CTLA-4) as B7-1 (CD80), but shares… (More)
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Highly Cited
1994
Highly Cited
1994
Antigen-specific T cell activation requires the engagement of the T cell receptor (TCR) with antigen as well as the engagement of… (More)
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Highly Cited
1994
Highly Cited
1994
B7-2 is a recently discovered, second ligand for the CTLA-4/CD28, T cell signaling system. Using the GL-1 rat monoclonal antibody… (More)
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