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CD86 wt Allele

Known as: CD28LG2, CD86 Antigen (CD28 Antigen Ligand 2, B7-2 Antigen) Gene, B70 
Human CD86 wild-type allele is located in the vicinity of 3q21 and is approximately 66 kb in length. This allele, which encodes T-lymphocyte… 
National Institutes of Health

Related topics

Related topics

6 relations
3q21Homo sapiensSignal TransductionT-Cell Proliferation

Broader (1)

CD86 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Immunogenicity and immunomodulatory effects of amnion-derived multipotent progenitor cells.
Review
2006
Review
2006
Mechanisms of CTLA-4-Ig in tolerance induction.
The size of the peripheral T lymphocyte pool remains relatively constant throughout adult life, but individual populations… 
2002
2002
Intense expression of the b7-2 antigen presentation coactivator is an unfavorable prognostic indicator for differentiated thyroid carcinoma of children and adolescents.
Previous observations suggest that an immune response against thyroid carcinoma could be important for long-term survival. We… 
2001
2001
[Cloning of B7-1 and B7-2 genes from human Burkitt's B lymphocyte line].
AIM In order to construct recombinant B7-Pseudomonas exotoxin fusion protein to induce long-term immunotolerance, we tried to… 
2000
2000
Molecular cloning of the cDNAs encoding the feline B-lymphocyte activation antigen B7-1 (CD80) and B7-2 (CD86) homologues which interact with human CTLA4-Ig.
We cloned the cDNAs encoding the feline homologues of B-lymphocyte activation antigens B7-1 (CD80) and B7-2 (CD86). We expressed… 
1999
1999
Differential effects of B7‐1 and B7‐2 on the costimulation of mouse nonspecific cytotoxic T lymphocyte development in response to anti‐CD3 antibody
Despite extensive study, the relative contribution of B7‐1 and B7‐2 molecules to the costimulation of cytotoxic T lymphocyte (CTL… 
Highly Cited
1997
Highly Cited
1997
Split activity of interleukin‐10 on antigen capture and antigen presentation by human dendritic cells: Definition of a maturative step
Human CD1+ CD14‐ dendritic cells (DC) can be derived from CD14+ monocytes using granulocyte/monocyte colony‐stimulating factor… 
Highly Cited
1997
Highly Cited
1997
Immunomodulatory effects of a plasmid expressing B7‐2 on human immunodeficiency virus‐1‐specific cell‐mediated immunity induced by a plasmid encoding the viral antigen
B7 co‐stimulation is essential for activating resting T cells following antigen recognition by the T cell receptor. To determine… 
Highly Cited
1996
Highly Cited
1996
Expression of costimulatory molecules in human leukemias.
In order to determine the indication of B7 (B7-1 and B7-2) molecules-mediated immuno-gene therapy for human leukemias, we… 
Highly Cited
1993
Highly Cited
1993
Structural heterogeneity in HLA-B70, a high-frequency antigen of black populations.
Although the B70 antigen exhibits allele frequencies of 8-23% in African and American black populations, it remains poorly… 
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